2024
Adolescent brain maturation associated with environmental factors: a multivariate analysis
Ray B, Jensen D, Suresh P, Thapaliya B, Sapkota R, Farahdel B, Fu Z, Chen J, Calhoun V, Liu J. Adolescent brain maturation associated with environmental factors: a multivariate analysis. Frontiers In Neuroimaging 2024, 3: 1390409. DOI: 10.3389/fnimg.2024.1390409.Peer-Reviewed Original ResearchLeft medial orbitofrontal cortexReduced gray matter densityMedial orbitofrontal cortexMiddle temporal gyrusGray matter densityIncreased functional connectivityIncrease cognitive performanceSusceptible to environmental influencesBilateral occipital regionsDelayed brain maturationIncreased cortical thicknessOrbitofrontal cortexAdolescent brainHuman adolescentsTemporal gyrusBrain characteristicsCognitive performanceBrain regionsBrain age estimationBrain metricsFunctional connectivityBrain agingBrain maturationBrain variationBrain modalities
2023
F71. NETWORK OF CO-METHYLATION ASSOCIATED WITH GREY MATTER MATURATION IN HUMAN ADOLESCENCE
Jensen D, Chen J, Turner J, Stephen J, Wang Y, Wilson T, Calhoun V, Liu J. F71. NETWORK OF CO-METHYLATION ASSOCIATED WITH GREY MATTER MATURATION IN HUMAN ADOLESCENCE. European Neuropsychopharmacology 2023, 75: s258-s259. DOI: 10.1016/j.euroneuro.2023.08.455.Peer-Reviewed Original ResearchStructural MRIBrain maturationNeuronal systemsCo-methylation network analysisPeriod of brain maturationAdolescent brain developmentAdolescent brain maturationPhases of neurodevelopmentIndependent component analysisGray matterHuman brain structureGM maturationDNAm changesCo-methylation modulesPrefrontal cortexExecutive functionFrontal poleGM volumeTime pointsSubjects aged 9Brain structuresCpG sitesSynaptic pruningBrain developmentDNA methylationEpigenetic associations with adolescent grey matter maturation and cognitive development
Jensen D, Chen J, Turner J, Stephen J, Wang Y, Wilson T, Calhoun V, Liu J. Epigenetic associations with adolescent grey matter maturation and cognitive development. Frontiers In Genetics 2023, 14: 1222619. PMID: 37529779, PMCID: PMC10390095, DOI: 10.3389/fgene.2023.1222619.Peer-Reviewed Original ResearchGM volume increaseGray matter maturationPatterns of brain maturationImprove cognitive performanceGray matterExecutive functionEpisodic memoryCognitive performanceCognitive testsBrain structuresProcessing speedBrain maturationCognitive AssessmentCognitive scoresBrain imagingAged 9BrainEpigenetic associationsAdolescentsLongitudinal cohortDNA methylationHuman neurodevelopmentDNA methylation of genesCytosine-phosphate-guanine (CpG) sitesBrain tissue