2023
The E-cigarette or Vaping Product Use–Associated Lung Injury Epidemic: Pathogenesis, Management, and Future Directions: An Official American Thoracic Society Workshop Report
Rebuli M, Rose J, Noël A, Croft D, Benowitz N, Cohen A, Goniewicz M, Larsen B, Leigh N, McGraw M, Melzer A, Penn A, Rahman I, Upson D, Alexander L, Ewart G, Jaspers I, Jordt S, Kligerman S, Loughlin C, McConnell R, Neptune E, Nguyen T, Pinkerton K, Witek T. The E-cigarette or Vaping Product Use–Associated Lung Injury Epidemic: Pathogenesis, Management, and Future Directions: An Official American Thoracic Society Workshop Report. Annals Of The American Thoracic Society 2023, 20: 1-17. PMID: 36584985, PMCID: PMC9819258, DOI: 10.1513/annalsats.202209-796st.Peer-Reviewed Original ResearchConceptsE-cigarettesClinical careOfficial American Thoracic Society Workshop ReportProduct use-associated lung injuryUse-associated lung injuryPublic healthAmerican Thoracic Society workshopSevere pulmonary illnessProspective clinical studyPediatric clinical carePublic health responseElectronic medical recordsBiomarkers of exposureIntegrated electronic medical recordsInjury epidemicLung injuryClinical followCase RegistryPulmonary illnessMedical recordsClinical studiesInhalational toxicityDrug Administration regulationsEVALIExogenous exposure
2018
Formation of flavorant–propylene Glycol Adducts With Novel Toxicological Properties in Chemically Unstable E-Cigarette Liquids
Erythropel HC, Jabba SV, DeWinter TM, Mendizabal M, Anastas PT, Jordt SE, Zimmerman JB. Formation of flavorant–propylene Glycol Adducts With Novel Toxicological Properties in Chemically Unstable E-Cigarette Liquids. Nicotine & Tobacco Research 2018, 21: 1248-1258. PMID: 30335174, PMCID: PMC6698951, DOI: 10.1093/ntr/nty192.Peer-Reviewed Original ResearchConceptsFlavor aldehydesSolvent componentsNuclear magnetic resonance spectroscopyNovel chemical speciesReaction productsPhysiological aqueous solutionE-cigarette liquidsReactive chemical systemsToxicological propertiesCommercial e-liquidsMagnetic resonance spectroscopyE-liquidsAqueous mediaPropylene glycolAqueous solutionPotential toxicological effectsNew compoundsUltraviolet spectroscopyChemical speciesChemical reactionsGas chromatographyChemical systemsResonance spectroscopyToxicological effectsAldehydes