2016
A framework for designing dynamic lp-ntPET studies to maximize the sensitivity to transient neurotransmitter responses to drugs: Application to dopamine and smoking
Wang S, Kim S, Cosgrove KP, Morris ED. A framework for designing dynamic lp-ntPET studies to maximize the sensitivity to transient neurotransmitter responses to drugs: Application to dopamine and smoking. NeuroImage 2016, 146: 701-714. PMID: 27743899, PMCID: PMC5321849, DOI: 10.1016/j.neuroimage.2016.10.019.Peer-Reviewed Original ResearchConceptsNeurotransmitter responsesCigarette smokingDrug stimuliDA releaseDA activationBolus injectionMild shorteningPET scansOptimal timingSmokingDopamine responsePET dataLp-ntPETDose limitTime courseSex differencesScansLoss of sensitivityBehavioral tasksDrugsLinear parametric neurotransmitter PETLower dose limitSuch responsesResponseStimuli
2014
Voxelwise lp‐ntPET for detecting localized, transient dopamine release of unknown timing: Sensitivity Analysis and Application to Cigarette Smoking in the PET Scanner
Kim SJ, Sullivan JM, Wang S, Cosgrove KP, Morris ED. Voxelwise lp‐ntPET for detecting localized, transient dopamine release of unknown timing: Sensitivity Analysis and Application to Cigarette Smoking in the PET Scanner. Human Brain Mapping 2014, 35: 4876-4891. PMID: 24700424, PMCID: PMC4303353, DOI: 10.1002/hbm.22519.Peer-Reviewed Original Research