2023
Distinct neural networks predict cocaine versus cannabis treatment outcomes
Lichenstein S, Kohler R, Ye F, Potenza M, Kiluk B, Yip S. Distinct neural networks predict cocaine versus cannabis treatment outcomes. Molecular Psychiatry 2023, 28: 3365-3372. PMID: 37308679, PMCID: PMC10713861, DOI: 10.1038/s41380-023-02120-0.Peer-Reviewed Original ResearchConceptsConnectome-based predictive modelingCognitive behavior therapyCognitive behavioral therapySubstance use disordersCannabis abstinenceNeural mechanismsBehavior therapyDistinct neural networksComputer-based trainingCannabis use disorderFMRI scanningNeural predictorsStudy 1Study 2Treatment outcomesContingency managementPrior workComparison subjectsNetwork strengthUse disordersNovel treatment targetsAbstinenceIndependent samplesCocaine abstinenceTreatment responders
2021
Systematic review of structural and functional neuroimaging studies of cannabis use in adolescence and emerging adulthood: evidence from 90 studies and 9441 participants
Lichenstein SD, Manco N, Cope LM, Egbo L, Garrison KA, Hardee J, Hillmer AT, Reeder K, Stern EF, Worhunsky P, Yip SW. Systematic review of structural and functional neuroimaging studies of cannabis use in adolescence and emerging adulthood: evidence from 90 studies and 9441 participants. Neuropsychopharmacology 2021, 47: 1000-1028. PMID: 34839363, PMCID: PMC8938408, DOI: 10.1038/s41386-021-01226-9.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsAdolescent cannabis usersCannabis-related harmsCannabis usersCannabis effectsAdolescent brain functionOngoing brain developmentFunctional neuroimaging studiesEffects of cannabisAdolescent brainNeuroimaging studiesNeural effectsPotential moderatorsNeural alterationsCannabis policy changesReduced perceptionSystematic reviewCannabis useCerebellar regionsAdolescenceBrain functionPreliminary evidenceFuture researchEarly interventionLong-term goalExtant literature