2022
Depression and/or PTSD Comorbidity Affects Response to Antidepressants in Those With Alcohol Use Disorder
Na PJ, Ralevski E, Jegede O, Wolfgang A, Petrakis IL. Depression and/or PTSD Comorbidity Affects Response to Antidepressants in Those With Alcohol Use Disorder. Frontiers In Psychiatry 2022, 12: 768318. PMID: 35058816, PMCID: PMC8765227, DOI: 10.3389/fpsyt.2021.768318.Peer-Reviewed Original ResearchPost-traumatic stress disorderAlcohol use disorderCo-occurring depressionHeavy drinking daysBetter drinking outcomesDrinking daysDiagnostic groupsDrinking outcomesDepressive symptomsUse disordersPercent heavy drinking daysPercent drinking daysRandomized control trialSerotonergic antidepressantsPTSD comorbidityControl trialDepression groupDepressive outcomesSignificant interactionOverall significant differenceDesipramineParoxetinePlaceboMedicationsComorbid MDD
2021
Posttraumatic Distress Symptoms and Their Response to Treatment in Adults With Prolonged Grief Disorder.
Na PJ, Adhikari S, Szuhany KL, Chen AZ, Suzuki RR, Malgaroli M, Robinaugh DJ, Bui E, Mauro C, Skritskaya NA, Lebowitz BD, Zisook S, Reynolds CF, Shear MK, Simon NM. Posttraumatic Distress Symptoms and Their Response to Treatment in Adults With Prolonged Grief Disorder. The Journal Of Clinical Psychiatry 2021, 82 PMID: 34000119, DOI: 10.4088/jcp.20m13576.Peer-Reviewed Original ResearchConceptsPosttraumatic stress symptomsPosttraumatic distress symptomsNonviolent deathsGrief disorderPosttraumatic stress disorderBereaved adultsPrimary diagnosisFunctional impairmentMixed-effects regressionPlaceboProlonged Grief DisorderGrief treatmentMajor life stressorsCitalopramSecondary analysisAntidepressant citalopramDistress symptomsStress disorderPoor functioningLife stressorsAdultsDisordersTreatmentStress symptomsSymptoms