2016
Sleep Perception and Misperception in Chronic Cocaine Users During Abstinence
Hodges SE, Pittman B, Morgan PT. Sleep Perception and Misperception in Chronic Cocaine Users During Abstinence. Sleep 2016, 40: zsw069. PMID: 28364419, PMCID: PMC5806585, DOI: 10.1093/sleep/zsw069.Peer-Reviewed Original ResearchConceptsChronic cocaine usersSleep state misperceptionWeeks of abstinenceTotal sleep timeOccult insomniaCocaine usersState misperceptionSleep onsetSleep timeCocaine-dependent personsInpatient research facilitySleep latencyDiary questionnairesSleep perceptionPolysomnographic sleep recordingsDiary measurementsAbstinenceTreatment studiesFinal awakeningMisperceptionsNight 3Objective worseningParticipantsInsomniaSleep recordingsSleep abnormalities associated with alcohol, cannabis, cocaine, and opiate use: a comprehensive review
Angarita GA, Emadi N, Hodges S, Morgan PT. Sleep abnormalities associated with alcohol, cannabis, cocaine, and opiate use: a comprehensive review. Addiction Science & Clinical Practice 2016, 11: 9. PMID: 27117064, PMCID: PMC4845302, DOI: 10.1186/s13722-016-0056-7.Peer-Reviewed Original ResearchChapter 21 Sleep and Cocaine
Angarita G, Canavan S, Hodges S, Morgan P. Chapter 21 Sleep and Cocaine. 2016, 220-228. DOI: 10.1016/b978-0-12-800212-4.00021-2.Peer-Reviewed Original ResearchPoor cognitive performanceChronic cocaine usersChapter 21 SleepObjective sleep abnormalitiesCocaine use disorderOccult insomniaCognitive performanceSleep architectureMood dysregulationSleep experiencesCocaine usersAbstinenceSleepSleep abnormalitiesInsomniaCocaineDisordersOutcomesExperienceDysregulationBetter outcomesProfound abnormalities
2013
Abstinence-related changes in sleep during treatment for cocaine dependence
Angarita GA, Canavan SV, Forselius E, Bessette A, Pittman B, Morgan PT. Abstinence-related changes in sleep during treatment for cocaine dependence. Drug And Alcohol Dependence 2013, 134: 343-347. PMID: 24315572, PMCID: PMC4396819, DOI: 10.1016/j.drugalcdep.2013.11.007.Peer-Reviewed Original ResearchConceptsTotal sleep timeExtended abstinenceOutpatient cognitive behavioral therapyAbstinence-related changesDecreased slow wave sleepInpatient substance abuse treatmentCognitive behavioral therapySleep timeCocaine usersPolysomnographic sleepChronic cocaine usersCocaine-dependent participantsSubstance abuse treatmentThrice weekly urine toxicologyBehavioral therapyWeeks of abstinenceOverall sleep qualityAbuse treatmentDays abstinentDependent participantsREM sleep latencySleep qualityCocaine dependenceSlow-wave sleepAbstinence
2008
Sleep architecture, cocaine and visual learning
Morgan PT, Pace‐Schott E, Sahul ZH, Coric V, Stickgold R, Malison RT. Sleep architecture, cocaine and visual learning. Addiction 2008, 103: 1344-1352. PMID: 18855824, PMCID: PMC3690941, DOI: 10.1111/j.1360-0443.2008.02233.x.Peer-Reviewed Original ResearchConceptsChronic cocaine usersVisual learningProgressive abstinenceVisual texture discrimination taskLate night REM sleepSlow wave activityAbstinence-related changesTexture discrimination taskCocaine usersSleep architectureCocaine useVisual performanceREM sleepOvernight enhancementDays of abstinenceDiscrimination taskCocaine self-administration sessionsSelf-administration sessionsCognitive functionChronic cocaine useLearning deficitsCognitive dysfunctionRapid eye movement (REM) sleepAbstinenceCocaine abstinenceCocaine Users Differ from Normals on Cognitive Tasks Which Show Poorer Performance During Drug Abstinence
Pace-Schott EF, Morgan PT, Malison RT, Hart CL, Edgar C, Walker M, Stickgold R. Cocaine Users Differ from Normals on Cognitive Tasks Which Show Poorer Performance During Drug Abstinence. The American Journal Of Drug And Alcohol Abuse 2008, 34: 109-121. PMID: 18161649, DOI: 10.1080/00952990701764821.Peer-Reviewed Original ResearchConceptsVerbal recognition memoryCocaine usersCocaine-dependent individualsCocaine-induced impairmentRecognition memoryCognitive tasksCognitive batteryCognitive changesDrug-free baselineDrug abstinenceAbstinencePoor performanceMemoryCocaine useDrug useDay cocaineNormative valuesAttentionCocaineTaskImpairmentIndividualsBatteriesInpatient studyPilot Study of Lorazepam and Tiagabine Effects on Sleep, Motor Learning, and Impulsivity in Cocaine Abstinence
Morgan PT, Malison RT. Pilot Study of Lorazepam and Tiagabine Effects on Sleep, Motor Learning, and Impulsivity in Cocaine Abstinence. The American Journal Of Drug And Alcohol Abuse 2008, 34: 692-702. PMID: 18850496, DOI: 10.1080/00952990802308221.Peer-Reviewed Original ResearchConceptsSleep-dependent learningCocaine-dependent personsEffects of lorazepamCognitive effectsCognitive functionMotor learningTotal sleep timeDependent learningImpulsivitySlow-wave sleepCocaine abstinenceSleep latencyAbstinenceSleep timeSleepDependent personsLearningLight sleepCognitionCocaine administrationSedative hypnoticsPilot studyLorazepamParticipantsDifferent GABA
2007
Cocaine and Sleep: Early Abstinence
Morgan PT, Malison RT. Cocaine and Sleep: Early Abstinence. The Scientific World JOURNAL 2007, 7: 223-230. PMID: 17982597, PMCID: PMC5900952, DOI: 10.1100/tsw.2007.209.Peer-Reviewed Original ResearchConceptsSubjective reportsCognitive performance declineCompulsive cocaine useCocaine useDiminished sleepWeeks of abstinenceEarly abstinenceSubjective measuresPerformance declineSleep disturbancesAbstinenceSleepIndication of recoveryRelevant literatureDisordersMeasuresCocaineSignificant deteriorationChronic useRelationshipDysregulation
2005
Sleep, sleep-dependent procedural learning and vigilance in chronic cocaine users: Evidence for occult insomnia
Morgan PT, Pace-Schott EF, Sahul ZH, Coric V, Stickgold R, Malison RT. Sleep, sleep-dependent procedural learning and vigilance in chronic cocaine users: Evidence for occult insomnia. Drug And Alcohol Dependence 2005, 82: 238-249. PMID: 16260094, DOI: 10.1016/j.drugalcdep.2005.09.014.Peer-Reviewed Original ResearchConceptsChronic cocaine usersSelf-report measuresProcedural learningSelf-reported sleepCocaine usersTotal sleep timeVigilance reaction timeSleep timeDays of abstinenceOccult insomniaElectrophysiological measuresCocaine self-administration sessionsSelf-administration sessionsImpaired vigilanceChronic insomniaSustained abstinenceSleep disturbancesAbstinenceReaction timeSlow wave activityLearningSleep latencyDays abstinenceSleepVigilance