2011
Microstructural and Functional Connectivity in the Developing Preterm Brain
Lubsen J, Vohr B, Myers E, Hampson M, Lacadie C, Schneider KC, Katz KH, Constable RT, Ment LR. Microstructural and Functional Connectivity in the Developing Preterm Brain. Seminars In Perinatology 2011, 35: 34-43. PMID: 21255705, PMCID: PMC3063450, DOI: 10.1053/j.semperi.2010.10.006.Peer-Reviewed Original ResearchConceptsPreterm birthPreterm brainTerm control subjectsDiffusion tensor imaging studyFunctional connectivity studiesPreterm neonatesNeurodevelopmental impairmentControl subjectsAxonal integrityImaging studiesCognitive deficitsFunctional connectivityNeural circuitryFractional anisotropyTask-based connectivityNeural connectivityBrainExhibit alterationsNeurobiological basisConnectivity studiesWidespread alterationsMicrostructural connectivityBirthChildrenAlterations
2010
Preterm birth results in alterations in neural connectivity at age 16 years
Mullen KM, Vohr BR, Katz KH, Schneider KC, Lacadie C, Hampson M, Makuch RW, Reiss AL, Constable RT, Ment LR. Preterm birth results in alterations in neural connectivity at age 16 years. NeuroImage 2010, 54: 2563-2570. PMID: 21073965, PMCID: PMC3020252, DOI: 10.1016/j.neuroimage.2010.11.019.Peer-Reviewed Original ResearchConceptsDiffusion tensor imagingAge 16 yearsPT subjectsBrain injuryLow birth weight preterm childrenTerm controlsUncinate fasciculusBilateral external capsuleFA valuesWeight preterm childrenNeonatal brain injuryLower fractional anisotropy valuesYears of ageBilateral uncinate fasciculusFractional anisotropy valuesRight uncinate fasciculusRight arcuate fasciculusWhite matter disorganizationAlternative neural pathwaysPreterm birthExternal capsuleInferior frontal gyrusPreterm childrenCorpus callosumHigh riskFunctional connectivity to a right hemisphere language center in prematurely born adolescents
Myers EH, Hampson M, Vohr B, Lacadie C, Frost SJ, Pugh KR, Katz KH, Schneider KC, Makuch RW, Constable RT, Ment LR. Functional connectivity to a right hemisphere language center in prematurely born adolescents. NeuroImage 2010, 51: 1445-1452. PMID: 20347043, PMCID: PMC2872040, DOI: 10.1016/j.neuroimage.2010.03.049.Peer-Reviewed Original ResearchConceptsFunctional connectivityWord Reading EfficiencyVerbal Comprehension IndexWechsler Intelligence ScaleRight supramarginal gyrusPeabody Picture VocabularyGreater cognitive deficitsPPVT-R scoresPhonological processingComprehension IndexLanguage tasksChildren-IIIIntelligence ScaleReading efficiencyLanguage deficitsPicture VocabularyWISC-IIISupramarginal gyrusCognitive outcomesNeurobiological basisHemisphere regionsCognitive deficitsWernicke's areaNeural activityLanguage processing
2009
Alterations in neural connectivity in preterm children at school age
Gozzo Y, Vohr B, Lacadie C, Hampson M, Katz KH, Maller-Kesselman J, Schneider KC, Peterson BS, Rajeevan N, Makuch RW, Constable RT, Ment LR. Alterations in neural connectivity in preterm children at school age. NeuroImage 2009, 48: 458-463. PMID: 19560547, PMCID: PMC2775072, DOI: 10.1016/j.neuroimage.2009.06.046.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingLanguage tasksWernicke's areaLanguage processingPeabody Individual Achievement TestRight inferior frontal gyrusPT childrenAuditory language functionsAuditory language taskCortical language regionsSchool ageInferior frontal gyrusReading comprehension testWechsler Intelligence ScalePeabody Picture VocabularyInferior parietal lobulePT subjectsSchool-aged childrenChildren-IIIComprehension testFrontal gyrusIntelligence ScalePicture VocabularyWISC-IIILanguage regions