Featured Publications
Amygdala downregulation training using fMRI neurofeedback in post-traumatic stress disorder: a randomized, double-blind trial
Zhao Z, Duek O, Seidemann R, Gordon C, Walsh C, Romaker E, Koller W, Horvath M, Awasthi J, Wang Y, O’Brien E, Fichtenholtz H, Hampson M, Harpaz-Rotem I. Amygdala downregulation training using fMRI neurofeedback in post-traumatic stress disorder: a randomized, double-blind trial. Translational Psychiatry 2023, 13: 177. PMID: 37230984, PMCID: PMC10209552, DOI: 10.1038/s41398-023-02467-6.Peer-Reviewed Original ResearchConceptsPost-traumatic stress disorderControl groupAmygdala activityPTSD treatmentDouble-blind clinical trialStress disorderDouble-blind trialSecondary outcome measurementsTrauma recallNeurofeedback trainingGreater improvementAmygdala controlsPotential clinical applicationsSymptom scoresActive groupClinical trialsTreatment successOutcome measurementsTrauma scriptsSymptom reductionNeurofeedback interventionPTSD symptomsFMRI neurofeedbackAmygdalaNeural markers
2016
Real-Time fMRI Neurofeedback with War Veterans with Chronic PTSD: A Feasibility Study
Gerin MI, Fichtenholtz H, Roy A, Walsh CJ, Krystal JH, Southwick S, Hampson M. Real-Time fMRI Neurofeedback with War Veterans with Chronic PTSD: A Feasibility Study. Frontiers In Psychiatry 2016, 7: 111. PMID: 27445868, PMCID: PMC4914513, DOI: 10.3389/fpsyt.2016.00111.Peer-Reviewed Original ResearchPost-traumatic stress disorderChronic post-traumatic stress disorderResting-state functional connectivity patternsReal-time functional magnetic resonanceStudy of efficacyReal-time fMRI neurofeedbackWar veteransFunctional connectivity patternsFunctional magnetic resonanceClinical improvementAvailable treatmentsTrauma scriptsSymptom reductionMeaningful improvementsNovel interventionsNF trainingStress disorderBrain connectivityNeurofeedback interventionAmygdala activityFMRI neurofeedbackCombat veteransInterventionVeteransFeasibility study