Featured Publications
Amygdala downregulation training using fMRI neurofeedback in post-traumatic stress disorder: a randomized, double-blind trial
Zhao Z, Duek O, Seidemann R, Gordon C, Walsh C, Romaker E, Koller W, Horvath M, Awasthi J, Wang Y, O’Brien E, Fichtenholtz H, Hampson M, Harpaz-Rotem I. Amygdala downregulation training using fMRI neurofeedback in post-traumatic stress disorder: a randomized, double-blind trial. Translational Psychiatry 2023, 13: 177. PMID: 37230984, PMCID: PMC10209552, DOI: 10.1038/s41398-023-02467-6.Peer-Reviewed Original ResearchConceptsPost-traumatic stress disorderControl groupAmygdala activityPTSD treatmentDouble-blind clinical trialStress disorderDouble-blind trialSecondary outcome measurementsTrauma recallNeurofeedback trainingGreater improvementAmygdala controlsPotential clinical applicationsSymptom scoresActive groupClinical trialsTreatment successOutcome measurementsTrauma scriptsSymptom reductionNeurofeedback interventionPTSD symptomsFMRI neurofeedbackAmygdalaNeural markers
2010
Functional connectivity between ventral prefrontal cortex and amygdala at low frequency in the resting state in bipolar disorder
Chepenik LG, Raffo M, Hampson M, Lacadie C, Wang F, Jones MM, Pittman B, Skudlarski P, Blumberg HP. Functional connectivity between ventral prefrontal cortex and amygdala at low frequency in the resting state in bipolar disorder. Psychiatry Research 2010, 182: 207-210. PMID: 20493671, PMCID: PMC2914819, DOI: 10.1016/j.pscychresns.2010.04.002.Peer-Reviewed Original ResearchConceptsVentral prefrontal cortexBipolar disorderFunctional connectivityPrefrontal cortexState functional magnetic resonance imagingRight ventral prefrontal cortexFunctional magnetic resonance imagingMagnetic resonance imagingWhole-brain analysisTrait abnormalityResonance imagingVentral striatumHealthy participantsAmygdalaCortexDisordersNegative correlationLow frequencyDysfunctionStriatumAbnormalities