Featured Publications
Treatment Outcomes With Licensed and Unlicensed Stimulant Doses for Adults With Attention-Deficit/Hyperactivity Disorder
Farhat L, Flores J, Avila-Quintero V, Polanczyk G, Cipriani A, Furukawa T, Bloch M, Cortese S. Treatment Outcomes With Licensed and Unlicensed Stimulant Doses for Adults With Attention-Deficit/Hyperactivity Disorder. JAMA Psychiatry 2024, 81: 157-166. PMID: 37878348, PMCID: PMC10600727, DOI: 10.1001/jamapsychiatry.2023.3985.Peer-Reviewed Original ResearchAttention-deficit/hyperactivity disorderLicensed dosesDose-response curveStimulant dosesClinical trialsTreatment outcomesRisk benefitHyperactivity disorderReduction of symptomsDrug Administration recommendationsAdverse eventsDose escalationLanguage restrictionsAdministration recommendationsUS FoodSymptomsDosesAdditional riskData extractionAdditional reductionADHD symptomsAdultsGreater reductionStimulantsRisk
2023
Systematic review and meta-analysis: Season of birth and schizophrenia risk
Coury S, Lombroso A, Avila-Quintero V, Taylor J, Flores J, Szejko N, Bloch M. Systematic review and meta-analysis: Season of birth and schizophrenia risk. Schizophrenia Research 2023, 252: 244-252. PMID: 36682315, DOI: 10.1016/j.schres.2022.12.016.Peer-Reviewed Original ResearchConceptsRisk of schizophreniaSummer birthWinter birthSystematic reviewBirth monthVitamin D deficiencyStratified subgroup analysisSchizophrenia riskEtiological risk factorsMonth of birthD deficiencySeason of birthEtiologic causesSubgroup analysisVirus exposureRisk factorsSchizophreniaMonthsBirthSignificant differencesRiskAssociation
2022
Parental age and the risk of bipolar disorder in the offspring: A systematic review and meta‐analysis
Polga N, de Barros P, Farhat LC, de Almeida K, Bloch MH, Lafer B. Parental age and the risk of bipolar disorder in the offspring: A systematic review and meta‐analysis. Acta Psychiatrica Scandinavica 2022, 145: 568-577. PMID: 35188977, DOI: 10.1111/acps.13418.Peer-Reviewed Original ResearchConceptsRisk of BDBipolar disorderMaternal ageOdds ratioParental ageReference categoryOlder maternal age groupsAge groupsPaternal age groupsMaternal age groupsWeb of ScienceObservational studySystematic reviewAgeFurther studiesRiskDisordersOffspringAssociationEffect size indexEMBASEGroupSize indexPubMedStudy
2021
Parental Age and the Risk for Alzheimer’s Disease in Offspring: Systematic Review and Meta-Analysis
Szejko N, Macul Ferreira de Barros P, Avila-Quintero VJ, Lombroso A, Bloch MH. Parental Age and the Risk for Alzheimer’s Disease in Offspring: Systematic Review and Meta-Analysis. Dementia And Geriatric Cognitive Disorders Extra 2021, 11: 140-150. PMID: 34178019, PMCID: PMC8216010, DOI: 10.1159/000515523.Peer-Reviewed Original ResearchAlzheimer's diseaseSystematic reviewParental ageRisk factorsPaternal ageRisk of ADLate Alzheimer's diseaseAdequate control groupsCohort studyPotential confoundersCommon causeCase controlControl groupElectronic databasesMeta-AnalysisVersion 16Significant associationDown syndromeDifferential riskDiseaseRelevant studiesAgeOlder parentsRiskMethodological limitations
2015
Meta-Analysis: Reduced Risk of Anxiety with Psychostimulant Treatment in Children with Attention-Deficit/Hyperactivity Disorder
Coughlin CG, Cohen SC, Mulqueen JM, Ferracioli-Oda E, Stuckelman ZD, Bloch MH. Meta-Analysis: Reduced Risk of Anxiety with Psychostimulant Treatment in Children with Attention-Deficit/Hyperactivity Disorder. Journal Of Child And Adolescent Psychopharmacology 2015, 25: 611-617. PMID: 26402485, PMCID: PMC4617411, DOI: 10.1089/cap.2015.0075.Peer-Reviewed Original ResearchConceptsRisk of anxietyAttention-deficit/hyperactivity disorderPsychostimulant treatmentSide effectsHyperactivity disorderPlacebo-controlled trialStratified subgroup analysisTreatment of childrenDuration of useRisk ratioSubgroup analysisPsychostimulant medicationPlaceboPubMed searchTrial designNumber of childrenHigh dosesStimulant typePsychostimulantsAnxiety symptomsTreatmentChildrenRiskSymptomsAnxiety