2021
Meta-Analysis: Hemodynamic Responses to Sub-anesthetic Doses of Ketamine in Patients With Psychiatric Disorders
Vankawala J, Naples G, Avila-Quintero VJ, Ramírez KL, Flores JM, Bloch MH, Dwyer JB. Meta-Analysis: Hemodynamic Responses to Sub-anesthetic Doses of Ketamine in Patients With Psychiatric Disorders. Frontiers In Psychiatry 2021, 12: 549080. PMID: 33841195, PMCID: PMC8024485, DOI: 10.3389/fpsyt.2021.549080.Peer-Reviewed Original ResearchTreatment-resistant depressionSub-anesthetic dosesPost-traumatic stress disorderKetamine treatmentBlood pressureObsessive-compulsive disorderKetamine dosesHemodynamic parametersPsychiatric disordersPsychiatric populationsAverage heart rate increaseKetamine/esketamineStratified subgroup analysisKetamine-induced changesPotential cardiovascular riskHeart rate increaseAdult psychiatric populationSignificant increaseAdult age groupsSub-anesthetic ketamineEsketamine treatmentCardiovascular riskKetamine infusionHemodynamic changesSBP increase
2019
Trim the fat: the role of omega-3 fatty acids in psychopharmacology
Nasir M, Bloch MH. Trim the fat: the role of omega-3 fatty acids in psychopharmacology. Therapeutic Advances In Psychopharmacology 2019, 9: 2045125319869791. PMID: 31489174, PMCID: PMC6713969, DOI: 10.1177/2045125319869791.Peer-Reviewed Original ResearchPost-traumatic stress disorderDepressive disorderAmerican Psychiatric AssociationFindings of RCTsRecent negative studiesSide effect profileFatty acid supplementationFatty acidsRandomized-controlled trialEvidence of efficacySubstantial methodological shortcomingsEvidence-based treatmentsImpulse control disordersIncomplete blindingHeterogeneous sample populationsBipolar maniaTreatment guidelinesCurrent guidelinesCardiovascular diseaseAcid supplementationNegative studiesPatient complianceUnipolar depressionIneffective treatmentPsychotic disorders
2015
Anxiety Disorder-Specific Predictors of Treatment Outcome in the Coordinated Anxiety Learning and Management (CALM) Trial
Jakubovski E, Bloch MH. Anxiety Disorder-Specific Predictors of Treatment Outcome in the Coordinated Anxiety Learning and Management (CALM) Trial. Psychiatric Quarterly 2015, 87: 445-464. PMID: 26563229, DOI: 10.1007/s11126-015-9399-6.Peer-Reviewed Original ResearchConceptsSocial anxiety disorderAnxiety disordersCoordinated Anxiety LearningAnxiety LearningPost-traumatic stress disorderSelf-efficacy expectanciesPositive treatment expectanciesGeneralized anxiety disorderTreatment outcomesStress disorderTreatment expectanciesSpecific treatment needsSocial supportPanic disorderDisordersLearningSocioeconomic statusPredictors