Differential antagonism of delta opioid agonists by naltrindole and its benzofuran analog (NTB) in mice: evidence for delta opioid receptor subtypes.
Sofuoglu M, Portoghese P, Takemori A. Differential antagonism of delta opioid agonists by naltrindole and its benzofuran analog (NTB) in mice: evidence for delta opioid receptor subtypes. Journal Of Pharmacology And Experimental Therapeutics 1991, 257: 676-80. PMID: 1851833.Peer-Reviewed Original ResearchConceptsAntinociceptive ED50Antinociceptive actionMorphine sulfateAntinociceptive assaysDelta-opioid receptor agonistDelta opioid receptor subtypesDelta-opioid subtypesOpioid receptor agonistsOpioid receptor subtypesSingle large doseDelta-opioid agonistsPretreatment of animalsOpioid subtypesOpioid agonistsSpinal sitesDifferential antagonismReceptor agonistReceptor subtypesAntinociceptive activityD-Ala2Large doseDSLETDPDPENaltrindoleAntagonist activity