Factors governing the activation of adoptively transferred donor T cells infused after allogeneic bone marrow transplantation in the mouse
Durakovic N, Radojcic V, Skarica M, Bezak K, Powell J, Fuchs E, Luznik L. Factors governing the activation of adoptively transferred donor T cells infused after allogeneic bone marrow transplantation in the mouse. Blood 2007, 109: 4564-4574. PMID: 17227829, PMCID: PMC1885486, DOI: 10.1182/blood-2006-09-048124.Peer-Reviewed Original ResearchConceptsDonor lymphocyte infusionDonor T cellsHost T cellsBone marrow transplantationT cellsHost chimerismHost APCsMarrow transplantationPrevious sensitizationAllogeneic bone marrow transplantationToll-like receptor ligandsGvH responseGVL reactivityLeukemia reactivityLymphocyte infusionMixed chimerismTLR ligandsHost antigensMurine modelVivo administrationCell activatorsHigh levelsAlloreactivityChimerismMHC