1996
Acute cocaine effects on absolute cerebral blood flow
Wallace E, Wisniewski G, Zubal G, vanDyck C, Pfau S, Smith E, Rosen M, Sullivan M, Woods S, Kosten T. Acute cocaine effects on absolute cerebral blood flow. Psychopharmacology 1996, 128: 17-20. PMID: 8944401, DOI: 10.1007/s002130050104.Peer-Reviewed Original ResearchConceptsRelative cerebral blood flowCerebral blood flowBlood flowWhole-brain blood flowAbsolute cerebral blood flowBrain blood flowBlood flow changesAcute cocaine effectsRelative blood flow changesCocaine effectsMean decreaseCocaine useCocaine usersSignificant decreaseFlow changesMicrosphere modelVasoconstrictionStroke
1995
Behavioral, physiological, and pharmacological interaction of cocaine and disulfiram in humans
Hameedi F, Rosen M, McCance-Katz E, McMahon T, Price L, Jatlow P, Woods S, Kosten T. Behavioral, physiological, and pharmacological interaction of cocaine and disulfiram in humans. Biological Psychiatry 1995, 37: 560-563. PMID: 7619981, DOI: 10.1016/0006-3223(94)00361-6.Peer-Reviewed Original ResearchOpiate Dependence and Withdrawal: Preliminary Assessment Using Single Photon Emission Computerized Tomography (SPECT)
Krystal J, Woods S, Kosten T, Rosen M, Seibyl J, Van Dyck C, Price L, Zubal I, Hoffer P, Charney D. Opiate Dependence and Withdrawal: Preliminary Assessment Using Single Photon Emission Computerized Tomography (SPECT). The American Journal Of Drug And Alcohol Abuse 1995, 21: 47-63. PMID: 7762544, DOI: 10.3109/00952999509095229.Peer-Reviewed Original ResearchConceptsRegional brain functionOpiate withdrawal signsSingle Photon Emission Computerized TomographyHealthy subjectsNaloxone administrationOpiate withdrawalOpiate dependenceBrain functionParietal cortexHexamethylpropyleneamine oximeWithdrawal signsNaloxone effectChronic opiate dependencePlacebo-controlled studyRegional alterationsComparison of patientsMethadone-maintained patientsRegional cerebral perfusionPhoton Emission Computerized TomographyOpiate-dependent patientsRight temporal cortexRight parietal cortexFunctional brain imaging technologiesSingle photon emissionEmission computerized tomography