Lack of efficacy of clozapine monotherapy in refractory obsessive- compulsive disorder
McDougle CJ, Barr LC, Goodman WK, Pelton GH, Aronson SC, Anand A, Price LH. Lack of efficacy of clozapine monotherapy in refractory obsessive- compulsive disorder. American Journal Of Psychiatry 1995, 152: 1812-1814. PMID: 8526253, DOI: 10.1176/ajp.152.12.1812.Peer-Reviewed Original ResearchConceptsTreatment-resistant obsessive-compulsive disorderRefractory obsessive-compulsive disorderGlobal improvement itemObsessive-compulsive disorderClozapine monotherapyClinical Global Impression ScaleHamilton Depression Rating ScaleMost adult patientsGlobal Impression ScaleDepression Rating ScaleLack of efficacyYale-Brown Obsessive Compulsive ScaleCGI global improvement itemObsessive Compulsive ScaleAdult patientsImpression ScaleDepressive symptomsImprovement itemsMonotherapyRating ScaleCompulsive ScaleDisordersPatientsTrialsEfficacy