Featured Publications
Mapping data‐driven individualized neurobehavioral phenotypes in heavy alcohol drinkers
DeMartini KS, Gueorguieva R, Pearlson G, Krishnan‐Sarin S, Anticevic A, Ji LJ, Krystal JH, O’Malley S. Mapping data‐driven individualized neurobehavioral phenotypes in heavy alcohol drinkers. Alcohol Clinical And Experimental Research 2021, 45: 841-853. PMID: 33605439, DOI: 10.1111/acer.14580.Peer-Reviewed Original ResearchConceptsConfirmatory factor analysisIncentive salienceNeurofunctional domainsAlcohol use disorderExecutive functionLatent factorsPhysical neglectSelf-report measuresChildhood emotional abuseUse disordersChildhood physical neglectEarly life stressSignificant predictorsMultiple significant predictorsMultiple causes modelCurrent AUDNegative emotionalityAddiction developmentEmotional abuseChildhood neglectFactor structureDrinking frequencySalienceCause modelFactor analysisSensitivity, specificity, and tolerability of the BACTrack Skyn compared to other alcohol monitoring approaches among young adults in a field‐based setting
Ash GI, Gueorguieva R, Barnett NP, Wang W, Robledo DS, DeMartini KS, Pittman B, Redeker NS, O’Malley S, Fucito LM. Sensitivity, specificity, and tolerability of the BACTrack Skyn compared to other alcohol monitoring approaches among young adults in a field‐based setting. Alcohol Clinical And Experimental Research 2022, 46: 783-796. PMID: 35567595, PMCID: PMC9179100, DOI: 10.1111/acer.14804.Peer-Reviewed Original ResearchDrinking Goals and Attainment in a Naltrexone Trial of Young Adult Heavy Drinkers
DeMartini KS, Foster DW, Corbin WR, Fucito LM, Romano D, Leeman RF, Kranzler HR, O’Malley S. Drinking Goals and Attainment in a Naltrexone Trial of Young Adult Heavy Drinkers. Journal Of Consulting And Clinical Psychology 2018, 86: 765-774. PMID: 30138015, PMCID: PMC6435339, DOI: 10.1037/ccp0000323.Peer-Reviewed Original ResearchConceptsTreatment outcomesAdult heavy drinkersYoung adult heavy drinkersHeavy drinkersDrinking goalEnd of treatmentPeak drinkingBetter treatment outcomesAlcohol use disorderImpact treatment outcomesTypical drinkingYoung adult drinkersEfficacy trialsUse disordersBrief counselingGoal settingIntervention effectsGoal-setting exercisesAdult drinkersDrinkersOutcomesDrinkingTreatmentImportant targetMidtreatment
2022
Within‐ and between‐person effects of naltrexone on the subjective response to alcohol and craving: A daily diary investigation
Waddell JT, Corbin WR, MacKinnon DP, Leeman RF, DeMartini KS, Fucito LM, Kranzler HR, O’Malley S. Within‐ and between‐person effects of naltrexone on the subjective response to alcohol and craving: A daily diary investigation. Alcohol Clinical And Experimental Research 2022, 46: 477-491. PMID: 35076087, PMCID: PMC9679805, DOI: 10.1111/acer.14780.Peer-Reviewed Original ResearchMeSH KeywordsAlcohol DrinkingAlcoholismCravingDouble-Blind MethodEthanolHumansNaltrexoneNarcotic AntagonistsYoung AdultConceptsMedication dosageYoung adultsLight drinkingSubjective responsesSubjective effectsHeavy drinkingPlacebo-controlled studyEffect sizePerson effectsEffective treatmentNaltrexoneDrinking daysNaltrexone efficacySmall effect sizesDrinking levelsCravingDrinkingAdultsLaboratory-based studiesPillsMomentary assessmentEfficacyTreatment conditionsDrinking environmentsDaily diary data
2021
Reward drinking and naltrexone treatment response among young adult heavy drinkers
Roos CR, Bold KW, Witkiewitz K, Leeman RF, DeMartini KS, Fucito LM, Corbin WR, Mann K, Kranzler HR, O'Malley SS. Reward drinking and naltrexone treatment response among young adult heavy drinkers. Addiction 2021, 116: 2360-2371. PMID: 33620746, PMCID: PMC8328878, DOI: 10.1111/add.15453.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAlcohol DrinkingAlcoholismBlood Alcohol ContentFemaleHumansMaleNaltrexoneRewardYoung Adult
2020
Using Web-Based Social Media to Recruit Heavy-Drinking Young Adults for Sleep Intervention: Prospective Observational Study
Ash GI, Robledo DS, Ishii M, Pittman B, DeMartini KS, O'Malley SS, Redeker NS, Fucito LM. Using Web-Based Social Media to Recruit Heavy-Drinking Young Adults for Sleep Intervention: Prospective Observational Study. Journal Of Medical Internet Research 2020, 22: e17449. PMID: 32780027, PMCID: PMC7448185, DOI: 10.2196/17449.Peer-Reviewed Original ResearchConceptsAlcohol use disorderSleep interventionsSleep concernsYoung adultsAlcohol useWeb-based surveyBrief web-based surveyProspective observational studyHeavy-drinking young adultsYears of ageHigh response rateAlcohol prevention strategiesHeavy alcohol useAlcohol prevention programsHeavy drinking young adultsScreening eligibilityRisk factorsStudy enrolleesObservational studySleep programSleep problemsAlcohol screenerUse disordersPrevention strategiesResponse rateDrinking and responses to antidrinking messages among young adults: An fMRI study
Garrison KA, DeMartini KS, Corlett PR, Worhunsky PD, Krystal JH, O'Malley SS. Drinking and responses to antidrinking messages among young adults: An fMRI study. Addiction Biology 2020, 26: e12882. PMID: 32068323, PMCID: PMC7431375, DOI: 10.1111/adb.12882.Peer-Reviewed Original ResearchConceptsDrinking cuesNeural responsesYoung adultsFunctional magnetic resonanceSelf-reported drinkingPast monthNeutral cuesDrug cuesSmoking cuesHabitual responsesReward processingFMRI studyDrinking quantityCuesDependent individualsSubstance useAlcohol useBinge drinkingNegative consequencesGreater baselinePublic health campaignsExcessive drinkingHeavy drinkingHealth campaignsDrinking
2019
The Association of Impulsivity and Family History of Alcohol Use Disorder on Alcohol Use and Consequences
Haeny AM, Gueorguieva R, Morean ME, Krishnan‐Sarin S, DeMartini KS, Pearlson GD, Anticevic A, Krystal JH, O'Malley SS. The Association of Impulsivity and Family History of Alcohol Use Disorder on Alcohol Use and Consequences. Alcohol Clinical And Experimental Research 2019, 44: 159-167. PMID: 31693193, PMCID: PMC6981005, DOI: 10.1111/acer.14230.Peer-Reviewed Original ResearchConceptsFacets of impulsivityBarratt Impulsiveness ScaleAlcohol-related problemsAlcohol use disorderProblem drinkingAssociation of impulsivityImpulsivity-related traitsAlcohol-related consequencesUse disordersFHP individualsAlcohol outcomesImpulsiveness ScaleImpulsivityProblematic drinkingFHN individualsDrinking quantityAlcohol quantityTranslational neuroscienceAlcohol misuseAlcohol useTransdisciplinary Tobacco Use Research CenterMain effectAnalysis of covariancePhenotypic riskStrong positive association
2018
The Self-Report Habit Index: Assessing habitual marijuana, alcohol, e-cigarette, and cigarette use
Morean ME, DeMartini KS, Foster D, Patock-Peckham J, Garrison KA, Corlett PR, Krystal JH, Krishan-Sarin S, O'Malley SS. The Self-Report Habit Index: Assessing habitual marijuana, alcohol, e-cigarette, and cigarette use. Drug And Alcohol Dependence 2018, 186: 207-214. PMID: 29609132, PMCID: PMC5912163, DOI: 10.1016/j.drugalcdep.2018.01.014.Peer-Reviewed Original ResearchA Test of Multisession Automatic Action Tendency Retraining to Reduce Alcohol Consumption Among Young Adults in the Context of a Human Laboratory Paradigm
Leeman RF, Nogueira C, Wiers RW, Cousijn J, Serafini K, DeMartini KS, Bargh JA, O'Malley SS. A Test of Multisession Automatic Action Tendency Retraining to Reduce Alcohol Consumption Among Young Adults in the Context of a Human Laboratory Paradigm. Alcohol Clinical And Experimental Research 2018, 42: 803-814. PMID: 29450895, PMCID: PMC5995797, DOI: 10.1111/acer.13613.Peer-Reviewed Original ResearchMeSH KeywordsAdultAlcohol DrinkingChoice BehaviorEducationEthanolFemaleHumansMaleSelf AdministrationYoung AdultConceptsHuman laboratory paradigmLaboratory paradigmApproach tendenciesControl conditionYoung adultsYoung adult heavy drinkingAlcohol-approach tendenciesAutomatic action tendenciesAlcohol-related stimuliYoung adults' alcohol consumptionAlcohol consumptionHeavy drinking young adultsLaboratory-based measuresAlcohol drinking sessionsAction tendenciesYoung adults ages 21Individual differencesImportant public health concernSelf-administration behaviorAdults ages 21Adult alcohol consumptionPublic health concernOnly modest effectsExperimental manipulationImpaired controlReciprocal Variations in Sleep and Drinking Over Time Among Heavy-Drinking Young Adults
Fucito LM, Bold KW, Van Reen E, Redeker NS, O’Malley S, Hanrahan TH, DeMartini KS. Reciprocal Variations in Sleep and Drinking Over Time Among Heavy-Drinking Young Adults. Journal Of Psychopathology And Clinical Science 2018, 127: 92-103. PMID: 29172601, PMCID: PMC5785424, DOI: 10.1037/abn0000312.Peer-Reviewed Original Research
2017
Using Sleep Interventions to Engage and Treat Heavy‐Drinking College Students: A Randomized Pilot Study
Fucito LM, DeMartini KS, Hanrahan TH, Yaggi HK, Heffern C, Redeker NS. Using Sleep Interventions to Engage and Treat Heavy‐Drinking College Students: A Randomized Pilot Study. Alcohol Clinical And Experimental Research 2017, 41: 798-809. PMID: 28118486, PMCID: PMC5378596, DOI: 10.1111/acer.13342.Peer-Reviewed Original ResearchConceptsHeavy-drinking college studentsAlcohol-related consequencesCollege studentsSleep interventionsGreater sleep improvementsBehavioral sleep interventionsHeavy drinking college studentsTreatment engagement strategiesHeavy-drinking studentsHigher alcohol consumption levelsSubsequent drinking outcomesWeb-based interventionSleep concernsEffective alcohol interventionsSleep treatmentsDrinking outcomesDrinking weekAlcohol interventionsSleep improvementImproved sleep qualitySleep contentControl conditionAlcohol consumption levelsAlcohol useRecruitment ads
2016
Urgency traits moderate daily relations between affect and drinking to intoxication among young adults
Bold KW, Fucito LM, DeMartini KS, Leeman RF, Kranzler HR, Corbin WR, O’Malley S. Urgency traits moderate daily relations between affect and drinking to intoxication among young adults. Drug And Alcohol Dependence 2016, 170: 59-65. PMID: 27875802, PMCID: PMC5183550, DOI: 10.1016/j.drugalcdep.2016.10.035.Peer-Reviewed Original ResearchConceptsYoung adultsHeavy drinkingEffectiveness of naltrexoneBlood alcohol concentrationHeavy drinking young adultsBrief motivational interventionNaltrexone treatmentClinical trialsHazardous drinkingNaltrexoneSecondary analysisPlaceboTargeted interventionsAge 18Alcohol useIntoxicationLow urgencyAdultsMotivational interventionDrinkingTrait urgencyOddsInterventionCurrent studyRiskRandomized Controlled Trial of a Very Brief, Multicomponent Web-Based Alcohol Intervention for Undergraduates With a Focus on Protective Behavioral Strategies
Leeman RF, DeMartini KS, Gueorguieva R, Nogueira C, Corbin WR, Neighbors C, O’Malley S. Randomized Controlled Trial of a Very Brief, Multicomponent Web-Based Alcohol Intervention for Undergraduates With a Focus on Protective Behavioral Strategies. Journal Of Consulting And Clinical Psychology 2016, 84: 1008-1015. PMID: 27599223, PMCID: PMC5332163, DOI: 10.1037/ccp0000132.Peer-Reviewed Original ResearchConceptsHeavy drinkingWeb-based alcohol interventionPast-month heavy drinkingPeak drinkingControl conditionAlcohol-related problemsBrief interventionAlcohol interventionsYoung adultsInterventionWeeksSignificant differencesDrinkingMonthsDrinksFocused listPBSAssessment controlResearch interventionsFirst studyCondition participantsDaily Relations Among Affect, Urge, Targeted Naltrexone, and Alcohol Use in Young Adults
Bold KW, Fucito LM, Corbin WR, DeMartini KS, Leeman RF, Kranzler HR, O’Malley S. Daily Relations Among Affect, Urge, Targeted Naltrexone, and Alcohol Use in Young Adults. Experimental And Clinical Psychopharmacology 2016, 24: 367-375. PMID: 27690505, PMCID: PMC5111359, DOI: 10.1037/pha0000090.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAffectAlcohol DrinkingCounselingCuesDouble-Blind MethodFemaleHumansMaleNaltrexoneYoung AdultConceptsYoung adultsDouble-blind clinical trialHeavy drinkingSerious public health problemDose of medicationPublic health problemAlcohol-related interventionsTargeted naltrexoneNaltrexone groupOpioid antagonistRisk factorsClinical trialsFamily historyNaltrexone effectsGreater oddsAlcohol consumptionHealth problemsAlcohol dependenceSecondary analysisPlaceboNaltrexoneNaltrexone's abilityAdultsMedicationsDrinkingLongitudinal Findings From a Randomized Clinical Trial of Naltrexone for Young Adult Heavy Drinkers
DeMartini KS, Gueorguieva R, Leeman RF, Corbin WR, Fucito LM, Kranzler HR, O’Malley S. Longitudinal Findings From a Randomized Clinical Trial of Naltrexone for Young Adult Heavy Drinkers. Journal Of Consulting And Clinical Psychology 2016, 84: 185-190. PMID: 26654213, PMCID: PMC4941818, DOI: 10.1037/ccp0000053.Peer-Reviewed Original ResearchConceptsPercent days abstinentFirst placebo-controlled trialPercent days heavy drinkingHeavy drinkingPlacebo-controlled trialLong-term outcomesHeavy drinking daysYoung adults ages 18Adults ages 18Naltrexone conditionActive medicationPlacebo groupPharmacotherapy trialsAdult heavy drinkersYoung adult heavy drinkersNonsignificant decreaseSignificant benefitsYear posttreatmentDays abstinentDrinking daysMost outcomesSingle interventionHeavy drinkersTreatment improvementAge 18
2015
Interactive and Indirect Effects of Anxiety and Negative Urgency on Alcohol‐Related Problems
Menary KR, Corbin WR, Leeman RF, Fucito LM, Toll BA, DeMartini K, O'Malley SS. Interactive and Indirect Effects of Anxiety and Negative Urgency on Alcohol‐Related Problems. Alcohol Clinical And Experimental Research 2015, 39: 1267-1274. PMID: 26031346, PMCID: PMC4490982, DOI: 10.1111/acer.12762.Peer-Reviewed Original ResearchConceptsNegative urgencyAlcohol problemsPotential moderatorsCoping-related drinking motivesDependence symptomsPrevention/intervention effortsNegative emotional statesIndirect effectsInteractive effectsAlcohol-related problemsCurrent cross-sectional studyAlcohol use disorderNegative affectDrinking motivesEmotional statesDrinking sampleModeration hypothesisIntervention effortsDirect interactive effectsAnxietyYoung adultsUse disordersLongitudinal dataModeratorPositive associationReduction of alcohol drinking in young adults by naltrexone: a double-blind, placebo-controlled, randomized clinical trial of efficacy and safety.
O'Malley SS, Corbin WR, Leeman RF, DeMartini KS, Fucito LM, Ikomi J, Romano DM, Wu R, Toll BA, Sher KJ, Gueorguieva R, Kranzler HR. Reduction of alcohol drinking in young adults by naltrexone: a double-blind, placebo-controlled, randomized clinical trial of efficacy and safety. The Journal Of Clinical Psychiatry 2015, 76: e207-13. PMID: 25742208, PMCID: PMC4442987, DOI: 10.4088/jcp.13m08934.Peer-Reviewed Original ResearchConceptsHeavy drinking daysBlood alcohol concentrationPercent days abstinentDrinking daysNumber of drinksYoung adultsDays abstinentPercent heavy drinking daysOutpatient research centerSafety of naltrexonePlacebo-controlled studySerious adverse eventsRisk-benefit ratioPercentage of daysAdverse eventsSecondary outcomesPrimary outcomeFrequency of drinkingOpioid antagonistAdult heavy drinkersAlcohol drinkingClinical trialsEvaluable samplesYoung adult heavy drinkersTreatment period
2014
Variations in Sleep Characteristics and Sleep-Related Impairment in At-Risk College Drinkers: A Latent Profile Analysis
DeMartini KS, Fucito LM. Variations in Sleep Characteristics and Sleep-Related Impairment in At-Risk College Drinkers: A Latent Profile Analysis. Health Psychology 2014, 33: 1164-1173. PMID: 25133844, PMCID: PMC4428320, DOI: 10.1037/hea0000115.Peer-Reviewed Original ResearchConceptsSleep-related impairmentSleep patternsSleep characteristicsAlcohol Use Disorders Identification Test-Consumption scoresIllicit substance useRisk college drinkersIncrease riskLevels of alcoholDaytime consequencesSubsequent validation analysisInsufficient sleepAlcohol consumptionHealth treatmentDrug useAlcohol assessmentCollege student drinkersCollege drinkersLater bedtimesAlcohol useSleepBehavior Problem ScaleSubstance useImpairmentDrinkersGreater alcohol useA New Look at Risk-Taking: Using a Translational Approach to Examine Risk-Taking Behavior on the Balloon Analogue Risk Task
DeMartini KS, Leeman RF, Corbin WR, Toll BA, Fucito LM, Lejuez CW, O’Malley S. A New Look at Risk-Taking: Using a Translational Approach to Examine Risk-Taking Behavior on the Balloon Analogue Risk Task. Experimental And Clinical Psychopharmacology 2014, 22: 444-452. PMID: 25069012, PMCID: PMC4392709, DOI: 10.1037/a0037421.Peer-Reviewed Original Research