2014
Tissue Specific Arterial Spin Labeling fMRI: A Superior Method for Imaging Cerebral Blood Flow in Aging and Disease
Qiu Y, Borogovac A, Laine A, Hirsch J, Asllani I. Tissue Specific Arterial Spin Labeling fMRI: A Superior Method for Imaging Cerebral Blood Flow in Aging and Disease. Annual International Conference Of The IEEE Engineering In Medicine And Biology Society (EMBC) 2014, 2014: 6687-6690. PMID: 25571530, DOI: 10.1109/embc.2014.6945162.Peer-Reviewed Original Research
2012
Sleep restriction leads to increased activation of brain regions sensitive to food stimuli
St-Onge MP, McReynolds A, Trivedi ZB, Roberts AL, Sy M, Hirsch J. Sleep restriction leads to increased activation of brain regions sensitive to food stimuli. American Journal Of Clinical Nutrition 2012, 95: 818-824. PMID: 22357722, PMCID: PMC3302360, DOI: 10.3945/ajcn.111.027383.Peer-Reviewed Original ResearchConceptsFood stimuliNeuronal activityHabitual sleepSleep restrictionNormal-weight menOverall neuronal activityAverage sleep durationFunctional magnetic resonance imagingMagnetic resonance imagingPartial sleep restrictionCrossover studyEpidemiologic evidenceClinical studiesNeuronal activationNucleus accumbensSleep durationFasted stateResonance imagingBrain regionsDay 6Prefrontal cortexSleepBrain activityRelative increaseStimuli
2011
Differences in Regional Brain Activation Patterns Assessed by Functional Magnetic Resonance Imaging in Patients with Systemic Lupus Erythematosus Stratified by Disease Duration
Mackay M, Bussa MP, Aranow C, Uluğ AM, Volpe BT, Huerta PT, Argyelan M, Mandel A, Hirsch J, Diamond B, Eidelberg D. Differences in Regional Brain Activation Patterns Assessed by Functional Magnetic Resonance Imaging in Patients with Systemic Lupus Erythematosus Stratified by Disease Duration. Molecular Medicine 2011, 17: 1349-1356. PMID: 21953419, PMCID: PMC3321819, DOI: 10.2119/molmed.2011.00185.Peer-Reviewed Original ResearchConceptsSystemic lupus erythematosusBlood-brain barrierFunctional magnetic resonance imagingTissue damageDisease durationBrain activation patternsLupus erythematosusST groupSystemic Lupus International Collaborating Clinics Damage IndexActivation patternsFearful face paradigmRegional brain activation patternsDuration of diseaseRegional brain abnormalitiesCentral nervous systemMagnetic resonance imagingFunctional magnetic resonanceCorticosteroid dosesDisease activityComorbid diseasesSLE patientsImmune cellsVascular diseaseBrain injuryBrain abnormalities