2012
The temporal derivative of expected utility: A neural mechanism for dynamic decision-making
Zhang X, Hirsch J. The temporal derivative of expected utility: A neural mechanism for dynamic decision-making. NeuroImage 2012, 65: 223-230. PMID: 22963852, PMCID: PMC5841235, DOI: 10.1016/j.neuroimage.2012.08.063.Peer-Reviewed Original ResearchConceptsNeural mechanismsBehavioral dataHuman neural correlatesNovel experimental paradigmDistinct neural activitySuperior parietal lobulePosterior cingulate cortexReal-world tasksNeural correlatesFuture rewardsParietal lobuleExperimental paradigmFMRI analysisCingulate cortexNeural activityWorld tasksBrain regionsSupplementary motorCentral gyrusDynamic decision processIndependent manipulationContinuous decisionsDecision processVentral pallidumFMRI
2008
Functional Imaging with Reinforcement, Eyetracking, and Physiological Monitoring
Ferrera V, Grinband J, Teichert T, Pestilli F, Dashnaw S, Hirsch J. Functional Imaging with Reinforcement, Eyetracking, and Physiological Monitoring. Journal Of Visualized Experiments 2008, 992. PMID: 19066528, PMCID: PMC2731772, DOI: 10.3791/992.Peer-Reviewed Original ResearchMeSH KeywordsBrainDecision MakingEye MovementsHumansMagnetic Resonance ImagingNeural PathwaysReinforcement, PsychologyConceptsHeart rateFMRI signalsAutonomic pathwaysFunctional brain imagingSimple perceptual tasksNeural circuitsFunctional imagingBrain imagingNeural activityPerceptual tasksUse of reinforcersAversive reinforcementSignal changesHead movementsReinforcer deliveryImagingPhysiological monitoringReinforcersAirpuffBrain
2007
Preparatory neural activity predicts performance on a conflict task
Stern ER, Wager TD, Egner T, Hirsch J, Mangels JA. Preparatory neural activity predicts performance on a conflict task. Brain Research 2007, 1176: 92-102. PMID: 17889835, PMCID: PMC2288660, DOI: 10.1016/j.brainres.2007.07.060.Peer-Reviewed Original ResearchConceptsPreparatory neural activityBilateral parietal cortexPreparatory activationNeutral cuesNeural activityParietal cortexRight dorsolateral prefrontal cortexReaction timeSpatial Stroop taskTask-relevant informationConflict resolutionDorsolateral prefrontal cortexTask-specific networksEfficient conflict resolutionConflict stimuliAdvance cuesCueing effectsStroop taskConflict taskAdvance cueingInformative cuesAnterior prefrontalLittle empirical workSemantic cuesPrefrontal cortex
2005
Cognitive control mechanisms resolve conflict through cortical amplification of task-relevant information
Egner T, Hirsch J. Cognitive control mechanisms resolve conflict through cortical amplification of task-relevant information. Nature Neuroscience 2005, 8: 1784-1790. PMID: 16286928, DOI: 10.1038/nn1594.Peer-Reviewed Original ResearchMeSH KeywordsAdultAttentionBehaviorBrain MappingCerebral CortexCerebrovascular CirculationCognitionConflict, PsychologicalDecision MakingFemaleFunctional LateralityHumansMagnetic Resonance ImagingMaleNerve NetNeural PathwaysNeuropsychological TestsPattern Recognition, VisualPhotic StimulationPrefrontal CortexReaction TimeVisual CortexVolitionConceptsTask-relevant informationCognitive control mechanismsTask-irrelevant informationCognitive controlTask-relevant stimulus informationCognitive control systemConflict resolutionDorsolateral prefrontal cortexHuman visual cortexAttentional biasingFace processingPerceptual processingFace stimuliStroop taskNeural representationStimulus informationResponse tendenciesOccurrence of conflictsHigh conflictPrefrontal cortexProminent modelsCortical responsesTrial levelCortical amplificationVisual cortexFunctional Specialization within the Medial Frontal Gyrus for Perceptual Go/No-Go Decisions Based on What, When, and Where Related Information: An fMRI Study
Talati A, Hirsch J. Functional Specialization within the Medial Frontal Gyrus for Perceptual Go/No-Go Decisions Based on What, When, and Where Related Information: An fMRI Study. Journal Of Cognitive Neuroscience 2005, 17: 981-993. PMID: 16102231, DOI: 10.1162/0898929054475226.Peer-Reviewed Original Research