2014
Brief Report: Anomalous Neural Deactivations and Functional Connectivity During Receptive Language in Autism Spectrum Disorder: A Functional MRI Study
Karten A, Hirsch J. Brief Report: Anomalous Neural Deactivations and Functional Connectivity During Receptive Language in Autism Spectrum Disorder: A Functional MRI Study. Journal Of Autism And Developmental Disorders 2014, 45: 1905-1914. PMID: 25526952, PMCID: PMC4441908, DOI: 10.1007/s10803-014-2344-y.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderNegative BOLD responseASD participantsReceptive languageLanguage disabilitySpectrum disorderNeural deactivationInhibitory processesFunctional connectivityFunctional magnetic resonance imagingBlood oxygen level-dependent (BOLD) responseSuperior temporal gyrusFunctional MRI studyLevel-dependent responsesNeural mechanismsPassive listeningTemporal gyrusBOLD responseControl participantsParticipantsLanguageMagnetic resonance imagingExcitatory processesMRI studiesConnectivity
2012
Neural systems for speech and song in autism
Lai G, Pantazatos SP, Schneider H, Hirsch J. Neural systems for speech and song in autism. Brain 2012, 135: 961-975. PMID: 22298195, PMCID: PMC3286324, DOI: 10.1093/brain/awr335.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAgingAnisotropyAttentionAutistic DisorderBrainChildDiffusion Tensor ImagingFemaleFunctional LateralityHead MovementsHumansImage Processing, Computer-AssistedInterview, PsychologicalLanguageMagnetic Resonance ImagingMaleMusicNerve NetNeural PathwaysNeuropsychological TestsPhotic StimulationRecruitment, NeurophysiologicalSpeechYoung AdultConceptsInferior frontal gyrusLeft inferior frontal gyrusFrontal gyrusAutistic childrenNeural systemsArcuate fasciculusFunctional magnetic resonanceSuperior temporal gyrusAge-matched control childrenLeft arcuate fasciculusPassive auditory stimulationMusic abilityLanguage disabilitySong conditionTemporal gyrusSpeech stimulationAuditory stimulationAutismFunctional connectivityNeural organizationBrain regionsSpeechControl childrenGyrusAutistic
2011
Can Depression be Diagnosed by Response to Mother's Face? A Personalized Attachment-Based Paradigm for Diagnostic fMRI
Zhang X, Yaseen ZS, Galynker II, Hirsch J, Winston A. Can Depression be Diagnosed by Response to Mother's Face? A Personalized Attachment-Based Paradigm for Diagnostic fMRI. PLOS ONE 2011, 6: e27253. PMID: 22180777, PMCID: PMC3236742, DOI: 10.1371/journal.pone.0027253.Peer-Reviewed Original ResearchConceptsBDI-II scoresFunctional magnetic resonance imagingBeck Depression Inventory-IIMagnetic resonance imagingResonance imagingInventory-IIBeck Depression Inventory-II scoresMINI psychiatric interviewII scoreDepression diagnosisPsychiatric interviewBA 32Paracingulate gyrusDepressed subjectsActivity patternsClinical diagnosisBrain reactivitySensitivity 85.7Diagnostic algorithmFemale subjectsDepressionSpecificity 92.8FMRI imagingScoresBrain activitySpeech Stimulation during Functional MR Imaging as a Potential Indicator of Autism
Lai G, Schneider HD, Schwarzenberger JC, Hirsch J. Speech Stimulation during Functional MR Imaging as a Potential Indicator of Autism. Radiology 2011, 260: 521-30. PMID: 21628495, DOI: 10.1148/radiol.11101576.Peer-Reviewed Original ResearchConceptsSuperior temporal gyrusControl subjectsSpeech stimulationFunctional MR imagingFunctional MR imaging activationFunctional magnetic resonanceAutistic subjectsMR imagingPrimary auditory cortexWilcoxon rank sum testInstitutional review boardMagnetic resonanceSpread of activityTwo-sample t-testRank sum testUnivariate general linear model analysisProspective studyMR evaluationAuditory cortexGeneral linear model analysisControl groupObjective indicatorsTemporal gyrusInformed consentReview board
2010
Analysis of clamping versus cutting of T3 sympathetic nerve for severe palmar hyperhidrosis
Yanagihara TK, Ibrahimiye A, Harris C, Hirsch J, Gorenstein LA. Analysis of clamping versus cutting of T3 sympathetic nerve for severe palmar hyperhidrosis. Journal Of Thoracic And Cardiovascular Surgery 2010, 140: 984-989. PMID: 20951250, PMCID: PMC2964926, DOI: 10.1016/j.jtcvs.2010.08.014.Peer-Reviewed Original ResearchConceptsEndoscopic thoracic sympathectomyPalmar hyperhidrosisSympathetic chainQuality of lifeThoracic sympathectomySevere palmar hyperhidrosisT3 sympathectomySympathetic nervesChief complaintPatient satisfactionExcessive sweatingPatientsSympathectomyT3 levelsHyperhidrosisSymptomsHigh rateSeverityClamping techniqueClampingNerveSurgerySweatingThighComplaints
2000
An Integrated Functional Magnetic Resonance Imaging Procedure for Preoperative Mapping of Cortical Areas Associated with Tactile, Motor, Language, and Visual Functions
Hirsch J, Ruge M, Kim K, Correa D, Victor J, Relkin N, Labar D, Krol G, Bilsky M, Souweidane M, DeAngelis L, Gutin P. An Integrated Functional Magnetic Resonance Imaging Procedure for Preoperative Mapping of Cortical Areas Associated with Tactile, Motor, Language, and Visual Functions. Neurosurgery 2000, 47: 711. PMID: 10981759, DOI: 10.1097/00006123-200009000-00037.Peer-Reviewed Original ResearchConceptsIntraoperative electrophysiological measurementsVisual field examinationVisual functionHealthy volunteersCentral sulcusVisual cortexFMRI mapsWernicke's areaFunctional magnetic resonance imaging (fMRI) taskDirect cortical stimulationFunctional magnetic resonance imaging (fMRI) procedureBroca's areaField examinationElectrophysiological measurementsSurgical patientsSurgical riskCortical stimulationPreoperative mappingSurgical routeWada testCortical areasElectrophysiological proceduresMagnetic resonance imaging (MRI) proceduresMultiple critical functionsPreoperative map
1999
Brain Mapping in Sedated Infants and Young Children with Passive-Functional Magnetic Resonance Imaging
Souweidane M, Kim K, McDowall R, Ruge M, Lis E, Krol G, Hirsch J. Brain Mapping in Sedated Infants and Young Children with Passive-Functional Magnetic Resonance Imaging. Pediatric Neurosurgery 1999, 30: 86-92. PMID: 10325564, DOI: 10.1159/000028768.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingMagnetic resonance imagingSedated childrenResonance imagingBrain mappingDiagnostic MRI scanYoung childrenLevel-dependent signalEarly developmental statusPediatric patientsPatient complianceMRI scansSedated infantsCortical regionsPatient interactionsFMRI techniquesFrequent needFMRI procedureLanguage functionChildrenInfantsDevelopmental statusPassive stimuliImagingStandard techniquesConcordance between Functional Magnetic Resonance Imaging and Intraoperative Language Mapping
Ruge M, Victor J, Hosain S, Correa D, Relkin N, Tabar V, Brennan C, Gutin P, Hirsch J. Concordance between Functional Magnetic Resonance Imaging and Intraoperative Language Mapping. Stereotactic And Functional Neurosurgery 1999, 72: 95-102. PMID: 10853058, DOI: 10.1159/000029706.Peer-Reviewed Original ResearchConceptsDirect cortical stimulationIntraoperative electrophysiologyCortical stimulationSensorimotor cortexIntraoperative language mappingFunctional magnetic resonance imagingMagnetic resonance imagingSSEP recordingsLocalization of functionMotor cortexIntraoperative localizationPreoperative toolResonance imagingLanguage mappingCortexWernicke's areaElectrophysiologyFMRIPresent studyStimulationSensorimotor mappingConcordancePatientsBroca
1982
Oculomotor Functions in Reading Disability
POYNTER H, SCHOR C, HAYNES H, HIRSCH J. Oculomotor Functions in Reading Disability. Optometry And Vision Science 1982, 59: 116-127. PMID: 7065104, DOI: 10.1097/00006324-198202000-00002.Peer-Reviewed Original ResearchConceptsReading abilityVerbal intelligenceOculomotor functionReciprocal-causation modelReading disabilityReading conditionsGrade childrenReading skillsFrequency of fixationsOculomotorInformation processing systemsSignificant relationReadingAbilityIntelligenceIndividual relationsAge groupsDisabilityChildren