2013
Reduced Anterior Temporal and Hippocampal Functional Connectivity During Face Processing Discriminates Individuals with Social Anxiety Disorder from Healthy Controls and Panic Disorder, and Increases Following Treatment
Pantazatos SP, Talati A, Schneier FR, Hirsch J. Reduced Anterior Temporal and Hippocampal Functional Connectivity During Face Processing Discriminates Individuals with Social Anxiety Disorder from Healthy Controls and Panic Disorder, and Increases Following Treatment. Neuropsychopharmacology 2013, 39: 425-434. PMID: 24084831, PMCID: PMC3870777, DOI: 10.1038/npp.2013.211.Peer-Reviewed Original ResearchConceptsSocial anxiety disorderFunctional connectivityAnxiety disordersFace perceptionTemporal poleFunctional magnetic resonance imaging studyPanic disorderSpecific anxiety disordersIndependent replication sampleHippocampal functional connectivityMagnetic resonance imaging studyFace processingPerceptual tasksResonance imaging studyBrain activationSAD diagnosisReplication sampleHIGH-SADSAD samplesSimilar tasksDisorder-specific biomarkersFC featuresSymptom severityAnterior temporalPerception
2012
Gray Matter Abnormalities in Social Anxiety Disorder: Primary, Replication, and Specificity Studies
Talati A, Pantazatos SP, Schneier FR, Weissman MM, Hirsch J. Gray Matter Abnormalities in Social Anxiety Disorder: Primary, Replication, and Specificity Studies. Biological Psychiatry 2012, 73: 75-84. PMID: 22748614, PMCID: PMC3465490, DOI: 10.1016/j.biopsych.2012.05.022.Peer-Reviewed Original ResearchConceptsControl subjectsAnxiety disordersGray matter abnormalitiesHealthy control groupAge 30 yearsDSM-IV criteriaTotal intracranial volumeVoxel-based morphometryGray matter differencesMagnetic resonance imagingBilateral temporal poleLateral orbitofrontal cortexPanic disorder subjectsAngular cortexPD groupFunctional disturbancesNeuroanatomical abnormalitiesSocial anxiety disorderControl groupTemporal poleStructural abnormalitiesLifetime historyResonance imagingSAD groupIntracranial volume