Gray Matter Abnormalities in Social Anxiety Disorder: Primary, Replication, and Specificity Studies
Talati A, Pantazatos SP, Schneier FR, Weissman MM, Hirsch J. Gray Matter Abnormalities in Social Anxiety Disorder: Primary, Replication, and Specificity Studies. Biological Psychiatry 2012, 73: 75-84. PMID: 22748614, PMCID: PMC3465490, DOI: 10.1016/j.biopsych.2012.05.022.Peer-Reviewed Original ResearchConceptsControl subjectsAnxiety disordersGray matter abnormalitiesHealthy control groupAge 30 yearsDSM-IV criteriaTotal intracranial volumeVoxel-based morphometryGray matter differencesMagnetic resonance imagingBilateral temporal poleLateral orbitofrontal cortexPanic disorder subjectsAngular cortexPD groupFunctional disturbancesNeuroanatomical abnormalitiesSocial anxiety disorderControl groupTemporal poleStructural abnormalitiesLifetime historyResonance imagingSAD groupIntracranial volume