Hemodynamic Impairment as a Stimulus for Functional Brain Reorganization
Marshall RS, Krakauer JW, Matejovsky T, Zarahn E, Barnes A, Lazar RM, Hirsch J. Hemodynamic Impairment as a Stimulus for Functional Brain Reorganization. Cerebrovascular And Brain Metabolism Reviews 2006, 26: 1256-1262. PMID: 16421509, DOI: 10.1038/sj.jcbfm.9600274.Peer-Reviewed Original ResearchConceptsVasomotor reactivityHemodynamic impairmentMotor-related activityControl subjectsFunctional reorganizationMotor regionsLevel-dependent signal intensityAbnormal cerebral hemodynamicsTypical motor activitiesLarge vessel occlusionSubgroup of patientsBlood oxygen level-dependent (BOLD) signal intensityContralateral motor areasFunctional brain reorganizationCarbon dioxide inhalationSimple motor taskFunctional magnetic resonanceAbnormal vasoreactivityTranscranial DopplerBrain reorganizationVessel occlusionCerebral hemodynamicsHand contralateralMotor areaFocal lesions