Modified total lymphoid irradiation and low dose corticosteroids in progressive multiple sclerosis
Cook S, Devereux C, Troiano R, Wolansky L, Guarnaccia J, Haffty B, Bansil S, Goldstein J, Sheffet A, Zito G, Jotkowitz A, Boos J, Dowling P, Rohowsky-Kochan C, Volmer T. Modified total lymphoid irradiation and low dose corticosteroids in progressive multiple sclerosis. Journal Of The Neurological Sciences 1997, 152: 172-181. PMID: 9415539, DOI: 10.1016/s0022-510x(97)00189-5.Peer-Reviewed Original ResearchConceptsTotal lymphoid irradiationMultiple sclerosisLymphoid irradiationDuration of MSExpanded Disability Status ScaleProgressive formKaplan-Meier product-limit survival analysisLow-dose corticosteroidsLow-dose prednisoneProgressive multiple sclerosisPrimary study endpointDisability Status ScaleProduct-limit survival analysisDose corticosteroidsDose prednisoneIntravenous methylprednisolonePrednisone therapyTLI groupTLI patientsSystemic immunosuppressionPatient ageStudy endpointStudy entrySham groupStatus Scale