2008
Corpus callosum in maltreated children with posttraumatic stress disorder: A diffusion tensor imaging study
Jackowski AP, Douglas-Palumberi H, Jackowski M, Win L, Schultz RT, Staib LW, Krystal JH, Kaufman J. Corpus callosum in maltreated children with posttraumatic stress disorder: A diffusion tensor imaging study. Psychiatry Research 2008, 162: 256-261. PMID: 18296031, PMCID: PMC3771642, DOI: 10.1016/j.pscychresns.2007.08.006.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderCorpus callosumStress disorderPathophysiology of PTSDDiffusion tensor imaging studyHistory of traumaWhite matter developmentEffects of stressWhite matter tractsWhite matter integrityDiffusion tensor imagingStudies of adultsInterhemispheric projectionsPediatric studiesPrimary white matter tractPreclinical studiesNormal controlsPosterior corpusHippocampus atrophyImaging studiesBrain structuresTensor imagingFractional anisotropyCallosumChildren
2004
Cannabinoid ‘model’ psychosis, dopamine–cannabinoid interactions and implications for schizophrenia
D'souza D, Cho H, Perry E, Krystal J. Cannabinoid ‘model’ psychosis, dopamine–cannabinoid interactions and implications for schizophrenia. 2004, 142-165. DOI: 10.1017/cbo9780511543630.012.Peer-Reviewed Original ResearchReceptor dysfunctionCannabinoid compoundsCannabis consumptionPathophysiology of psychosisPathophysiology of schizophreniaRecent pharmacological studiesPrincipal psychoactive constituentEffects of exposurePostmortem studiesNormal controlsPsychotic symptomsPsychotic disordersPharmacological studiesPsychosisPsychoactive constituentPathophysiologyΔ9-tetrahydrocannabinolSchizophreniaCannabisDysfunctionAssociationPossible mechanismPatientsSymptomsPharmacological
1992
Startle gating deficits occur across prepulse intensities in schizophrenic patients
Grillon C, Ameli R, Charney D, Krystal J, Braff D. Startle gating deficits occur across prepulse intensities in schizophrenic patients. Biological Psychiatry 1992, 32: 939-943. PMID: 1467378, DOI: 10.1016/0006-3223(92)90183-z.Peer-Reviewed Original ResearchConceptsPrepulse inhibitionPrepulse stimulusSchizophrenic patientsStartle reflexControl groupStartle gating deficitsCentral inhibitory mechanismsDeficient prepulse inhibitionGating deficitsStartling stimulusNormal controlsPatientsReflexPrepulse intensityInhibitory mechanismFurther studiesStimuliInhibitionGroup