Relative Importance of 3‐Methoxy‐4‐Hydroxyphenylglycol and 3,4‐Dihydroxyphenylglycol as Norepinephrine Metabolites in Rat, Monkey, and Humans
Elsworth J, Roth R, Redmond D. Relative Importance of 3‐Methoxy‐4‐Hydroxyphenylglycol and 3,4‐Dihydroxyphenylglycol as Norepinephrine Metabolites in Rat, Monkey, and Humans. Journal Of Neurochemistry 1983, 41: 786-793. PMID: 6875564, DOI: 10.1111/j.1471-4159.1983.tb04809.x.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBrainChlorocebus aethiopsGas Chromatography-Mass SpectrometryGlycolsHumansMaleMethoxyhydroxyphenylglycolNorepinephrineRatsRats, Inbred StrainsSpecies SpecificityTissue DistributionConceptsBrain MHPGNorepinephrine metabolismDHPG concentrationsRat brainConcentration of MHPGPlasma of primatesMonkey CSFAcute administrationNorepinephrine metabolitePrimate CNSMHPGMonkey brainDihydroxyphenylglycolGas chromatographic-mass spectrometric assayUnconjugated formRatsBrainPiperoxaneSignificant correlationDesipramineHigher proportionHuman plasmaMonkeysMetabolitesMetabolism