1995
Co-Grafts in Dopamine-Depleted Primates: Preliminary Results and Theoretical Issues Related to Human Applications for Parkinson’s Disease
Sladek J, Elsworth J, Roth R, Blanchard B, Taylor J, Collier T, Redmond D. Co-Grafts in Dopamine-Depleted Primates: Preliminary Results and Theoretical Issues Related to Human Applications for Parkinson’s Disease. Altschul Symposia Series 1995, 219-230. DOI: 10.1007/978-1-4615-1929-4_18.Peer-Reviewed Original ResearchDopamine neuronsDisease patientsHuman dopamine neuronsNon-dopaminergic neuronsVentral mesencephalic graftsParkinson's disease patientsMesencephalic reticular formationHuman neural tissueDaily levodopaHost brainMesencephalic graftsMesencephalic tissueDorsal rapheVentral mesencephalonPatient 1Serotonergic neuronsVentral tegmentumPoor survivalEmbryonic mesencephalonReticular formationTrochlear nucleusRat brainRat striatumTrigeminal complexParkinson's disease
1984
Endogenous substrates and inhibitors of monoamine oxidase
Sandler M, Glover V, Elsworth J. Endogenous substrates and inhibitors of monoamine oxidase. 1984, 187-192. DOI: 10.1007/978-1-349-86029-6_28.Peer-Reviewed Original Research
1983
Relative Importance of 3‐Methoxy‐4‐Hydroxyphenylglycol and 3,4‐Dihydroxyphenylglycol as Norepinephrine Metabolites in Rat, Monkey, and Humans
Elsworth J, Roth R, Redmond D. Relative Importance of 3‐Methoxy‐4‐Hydroxyphenylglycol and 3,4‐Dihydroxyphenylglycol as Norepinephrine Metabolites in Rat, Monkey, and Humans. Journal Of Neurochemistry 1983, 41: 786-793. PMID: 6875564, DOI: 10.1111/j.1471-4159.1983.tb04809.x.Peer-Reviewed Original ResearchConceptsBrain MHPGNorepinephrine metabolismDHPG concentrationsRat brainConcentration of MHPGPlasma of primatesMonkey CSFAcute administrationNorepinephrine metabolitePrimate CNSMHPGMonkey brainDihydroxyphenylglycolGas chromatographic-mass spectrometric assayUnconjugated formRatsBrainPiperoxaneSignificant correlationDesipramineHigher proportionHuman plasmaMonkeysMetabolitesMetabolism