2018
Genetic influences on eight psychiatric disorders based on family data of 4 408 646 full and half-siblings, and genetic data of 333 748 cases and controls
Pettersson E, Lichtenstein P, Larsson H, Song J, Agrawal A, Børglum A, Bulik C, Daly M, Davis L, Demontis D, Edenberg H, Grove J, Gelernter J, Neale B, Pardiñas A, Stahl E, Walters J, Walters R, Sullivan P, Posthuma D, Polderman T. Genetic influences on eight psychiatric disorders based on family data of 4 408 646 full and half-siblings, and genetic data of 333 748 cases and controls. Psychological Medicine 2018, 49: 1166-1173. PMID: 30221610, PMCID: PMC6421104, DOI: 10.1017/s0033291718002039.Peer-Reviewed Original ResearchMeSH KeywordsAdultAlcoholismAnorexia NervosaAttention Deficit Disorder with HyperactivityAutism Spectrum DisorderBipolar DisorderCase-Control StudiesCohort StudiesDepressive Disorder, MajorFamilyFemaleGene-Environment InteractionGenotypeHumansMaleMental DisordersObsessive-Compulsive DisorderQuantitative Trait, HeritableSchizophreniaSchizophrenic PsychologySiblingsSwedenMultivariate Pattern Analysis of Genotype–Phenotype Relationships in Schizophrenia
Zheutlin AB, Chekroud AM, Polimanti R, Gelernter J, Sabb FW, Bilder RM, Freimer N, London ED, Hultman CM, Cannon TD. Multivariate Pattern Analysis of Genotype–Phenotype Relationships in Schizophrenia. Schizophrenia Bulletin 2018, 44: 1045-1052. PMID: 29534239, PMCID: PMC6101611, DOI: 10.1093/schbul/sby005.Peer-Reviewed Original ResearchConceptsMultivariate pattern analysisIndependent samplesVisual memoryCognitive endophenotypesPredictive strengthSchizophreniaMemoryIndividual variationPattern analysisSingle predictorCertain domainsDiscovery samplePsychiatric patientsPolygenic risk scoresPredictive powerScoresEndophenotypesPotential relationshipRelationshipRandom forestGenetic risk variantsLimited setPredictorsComprehensive setSamples
1991
No Linkage Between D2 Dopamine Receptor Gene Region and Schizophrenia
Moises H, Gelernter J, Giuffra L, Zarcone V, Wetterberg L, Civelli O, Kidd K, Cavalli-Sforza L, Grandy D, Kennedy J, Vinogradov S, Mauer J, Litt M, Sjögren B. No Linkage Between D2 Dopamine Receptor Gene Region and Schizophrenia. JAMA Psychiatry 1991, 48: 643-647. PMID: 2069495, DOI: 10.1001/archpsyc.1991.01810310061011.Peer-Reviewed Original Research