ANKRD7 and CYTL1 are novel risk genes for alcohol drinking behavior.
Chen XD, Xiong DH, Yang TL, Pei YF, Guo YF, Li J, Yang F, Pan F, Tan LJ, Yan H, Liu XG, Lei SF, Li X, Ning LL, Zhu XZ, Levy S, Kranzler HR, Farrer LA, Gelernter J, Recker RR, Deng HW. ANKRD7 and CYTL1 are novel risk genes for alcohol drinking behavior. Chinese Medical Journal 2012, 125: 1127-34. PMID: 22613542, PMCID: PMC4174677.Peer-Reviewed Original ResearchConceptsGenome-wide association studiesAlcohol-related phenotypesAssociation studiesUnrelated Caucasian subjectsGenome-wide significance levelAffymetrix 500K SNP arrayK SNP arrayNovel risk genesCaucasian nuclear familiesGWAS technologySuggestive statistical evidenceSNP arrayANKRD7GenesRisk genesSusceptibility genesUnrelated Chinese HansSusceptibility allelesCertain haplotypesComplex disorderReplication sampleEnvironmental factorsUnrelated CaucasiansPhenotypeChinese Han