2022
Genome-wide meta-analysis of alcohol use disorder in East Asians
Zhou H, Kalayasiri R, Sun Y, Nuñez YZ, Deng HW, Chen XD, Justice AC, Kranzler HR, Chang S, Lu L, Shi J, Sanichwankul K, Mutirangura A, Malison RT, Gelernter J. Genome-wide meta-analysis of alcohol use disorder in East Asians. Neuropsychopharmacology 2022, 47: 1791-1797. PMID: 35094024, PMCID: PMC9372033, DOI: 10.1038/s41386-022-01265-w.Peer-Reviewed Original ResearchConceptsAlcohol use disorderAlcohol dependenceUse disordersICD-9-CM diagnosisGenome-wide association studiesEast Asian subjectsElectronic health recordsPack yearsLeading causePolygenic risk scoresThai cohortRisk scoreAlcohol consumptionDSM-IVAsian subjectsCohortMillion Veteran Program sampleHealth recordsLarge genome-wide association studiesEast AsiansOngoing recruitmentRisk genesDisordersRisk lociSubjects
2020
Diagnostic Reliability and Validity of the Semi-Structured Assessment for Drug Dependence and Alcoholism (SSADDA) Chinese Version
Yang BZ, Wang LJ, Huang MC, Wang SC, Tsai MC, Huang YC, Nuñez YZ, Ng MH, Kranzler HR, Gelernter J, Chen CK. Diagnostic Reliability and Validity of the Semi-Structured Assessment for Drug Dependence and Alcoholism (SSADDA) Chinese Version. Complex Psychiatry 2020, 6: 62-67. PMID: 34882761, PMCID: PMC7923924, DOI: 10.1159/000511606.Peer-Reviewed Original ResearchSD diagnosisSemi-Structured AssessmentTest-retest reliabilityDependence diagnosisDrug dependenceΚ statisticDiagnostic reliabilityStructured Clinical InterviewCohen κ statisticChance-corrected agreementClinician versionSubstance dependence diagnosesNicotine dependencePsychiatric disordersClinical InterviewAlcohol dependenceDSM-IVDiagnosisSubstance useChinese versionOpioidsValid instrumentConcurrent validityKetamineMethamphetamine
2015
Inter-observer reliability of DSM-5 substance use disorders
Denis CM, Gelernter J, Hart AB, Kranzler HR. Inter-observer reliability of DSM-5 substance use disorders. Drug And Alcohol Dependence 2015, 153: 229-235. PMID: 26048641, PMCID: PMC4509850, DOI: 10.1016/j.drugalcdep.2015.05.019.Peer-Reviewed Original ResearchConceptsDSM-5 SUD diagnosesSUD diagnosisDSM-IV diagnosisLifetime moodInter-observer reliabilityDSM-5 substance use disordersDisorder diagnosisCo-occurring SUDSubstance use disorder diagnosisSubstance use disordersDSM-5 criteriaSemi-Structured AssessmentAnxiety disorder diagnosisLifetime SUDMild severityUse disordersDrug dependenceSevere disordersDSM-IVPercent agreementDiagnosisAnxiety disordersLifetime alcoholLimited evidenceDisorders
2014
DSM-5 Gambling Disorder: Prevalence and Characteristics in a Substance Use Disorder Sample
Rennert L, Denis C, Peer K, Lynch KG, Gelernter J, Kranzler HR. DSM-5 Gambling Disorder: Prevalence and Characteristics in a Substance Use Disorder Sample. Experimental And Clinical Psychopharmacology 2014, 22: 50-56. PMID: 24490711, PMCID: PMC4019046, DOI: 10.1037/a0034518.Peer-Reviewed Original ResearchConceptsSubstance Use Disorder SamplePathological gamblingGD diagnosisSemistructured psychiatric interviewFourth Edition diagnosisLogistic regression analysisGambling disorderDSM-5 diagnosisMultinomial logistic regression analysisDisorder sampleProspective studySUD sampleEdition diagnosisHigh prevalenceComorbid SUDPG criteriaPsychiatric interviewMental disordersDSM-IVSubstance dependenceDiagnosisPrevalenceStatistical ManualRegression analysisFifth edition
2012
Prevalence of DSM-IV and DSM-5 alcohol, cocaine, opioid, and cannabis use disorders in a largely substance dependent sample
Peer K, Rennert L, Lynch KG, Farrer L, Gelernter J, Kranzler HR. Prevalence of DSM-IV and DSM-5 alcohol, cocaine, opioid, and cannabis use disorders in a largely substance dependent sample. Drug And Alcohol Dependence 2012, 127: 215-219. PMID: 22884164, PMCID: PMC3727225, DOI: 10.1016/j.drugalcdep.2012.07.009.Peer-Reviewed Original ResearchConceptsSubstance use disordersSUD diagnosisDSM-IVDiagnosis of SUDDSM-5DSM-5 substance use disordersDSM-5 SUD diagnosesDiagnostic orphansSevere substance use disordersLimited diagnostic utilityDSM-5 diagnosisDSM-5 alcoholSemi-Structured AssessmentDSM-IV abuseDiagnostic switchLifetime presenceClinical careDiagnostic criteriaGreater prevalenceUse disordersDiagnostic utilityDependence diagnosisMental disordersDrug dependenceSubstance dependence