2024
Exploiting meta-analysis of genome-wide interaction with serum 25-hydroxyvitamin D to identify novel genetic loci associated with pulmonary function
Seo J, Gaddis N, Patchen B, Xu J, Barr R, O’Connor G, Manichaikul A, Gharib S, Dupuis J, North K, Cassano P, Hancock D. Exploiting meta-analysis of genome-wide interaction with serum 25-hydroxyvitamin D to identify novel genetic loci associated with pulmonary function. American Journal Of Clinical Nutrition 2024, 119: 1227-1237. PMID: 38484975, PMCID: PMC11130669, DOI: 10.1016/j.ajcnut.2024.03.007.Peer-Reviewed Original ResearchConceptsGenome-wide association studiesGenome-wide interactionsGWAS meta-analysesGenome-wide genotypingGenetic variant associationsPathway enrichment analysisGenetic architectureVariant associationsP38 MAPK pathwayAssociation studiesGene-environment interactionsBiological insightsGenetic variantsEnrichment analysisVariant signalsMeta-analyzed resultsMAPK pathwayBiological relevancePathwayForced vital capacityEvaluate interactive effectsMeta-analysesVariantsSmoking historyAssociated with FEV<sub>1</sub> an
2023
MULTI-ANCESTRY PHENOME-WIDE ASSOCIATION ANALYSES OF GENETIC LIABILITY FOR PROBLEMATIC ALCOHOL USE
Kember R, Johnson J, Johnston K, Lee H, Xu J, Davis L, Smoller J, Mallard T, Huckins L, Sanchez-Roige S, Kranzler H, Gelernter J, Zhou H. MULTI-ANCESTRY PHENOME-WIDE ASSOCIATION ANALYSES OF GENETIC LIABILITY FOR PROBLEMATIC ALCOHOL USE. European Neuropsychopharmacology 2023, 75: s10. DOI: 10.1016/j.euroneuro.2023.08.027.Peer-Reviewed Original Research