Social supports moderate the effects of child adversity on neural correlates of threat processing
Wymbs NF, Orr C, Albaugh MD, Althoff RR, O’Loughlin K, Holbrook H, Garavan H, Montalvo-Ortiz JL, Mostofsky S, Hudziak J, Kaufman J. Social supports moderate the effects of child adversity on neural correlates of threat processing. Child Abuse & Neglect 2020, 102: 104413. PMID: 32065988, PMCID: PMC8060780, DOI: 10.1016/j.chiabu.2020.104413.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingThreat processingAnterior cingulate cortexSocial supportEmotion regulationNeural correlatesEmotional Go-Nogo taskGo-NoGo taskPositive social supportChildren ages 7Forms of adversityKey brain regionsAdverse experiencesFacial stimuliThreat stimuliNeural processingBrain systemsBrain activationModerate adversitySevere adversityAnterior insulaConjunction analysisLeft amygdalaOrbitofrontal cortexActivation foci