2016
N-Acetylcysteine in the Treatment of Pediatric Tourette Syndrome: Randomized, Double-Blind, Placebo-Controlled Add-On Trial
Bloch MH, Panza KE, Yaffa A, Alvarenga PG, Jakubovski E, Mulqueen JM, Landeros-Weisenberger A, Leckman JF. N-Acetylcysteine in the Treatment of Pediatric Tourette Syndrome: Randomized, Double-Blind, Placebo-Controlled Add-On Trial. Journal Of Child And Adolescent Psychopharmacology 2016, 26: 327-334. PMID: 27027204, PMCID: PMC6445198, DOI: 10.1089/cap.2015.0109.Peer-Reviewed Original ResearchConceptsBenefit of NACEfficacy of NACYale Global Tic Severity ScaleAttention-deficit/hyperactivity disorderObsessive-compulsive disorderTourette syndromeN-acetylcysteineObsessive-compulsive spectrum disordersSide effectsRecent placebo-controlled trialPediatric Tourette syndromePlacebo-controlled trialCurrent pharmacological treatmentsTreatment of ticsTotal tic scoreSeverity of ticsSubstantial side effectsTic Severity ScaleYears of ageMinimal side effectsPediatric TSPrimary outcomeSecondary outcomesGlutamatergic systemPharmacological treatment
2008
Maternal brain response to own baby‐cry is affected by cesarean section delivery
Swain JE, Tasgin E, Mayes LC, Feldman R, Constable RT, Leckman JF. Maternal brain response to own baby‐cry is affected by cesarean section delivery. Journal Of Child Psychology And Psychiatry 2008, 49: 1042-1052. PMID: 18771508, PMCID: PMC3246837, DOI: 10.1111/j.1469-7610.2008.01963.x.Peer-Reviewed Original ResearchConceptsCesarean section deliveryMode of deliveryVD mothersSection deliveryMother's brainVaginal deliveryElective cesarean section deliveryMaternal brain responsesImmediate postpartum periodRight lenticular nucleusSuperior frontal cortexMedial fusiform gyrusBeck Depression InventorySuperior frontal gyrusFunctional magnetic resonance imagingMagnetic resonance imagingSuperior parietal lobeMiddle temporal gyrusEarly postpartumPostpartum periodLenticular nucleusPostpartum depressionFrontal cortexSpecific brain activationParietal lobe