2014
Tourette syndrome deep brain stimulation: A review and updated recommendations
Schrock LE, Mink JW, Woods DW, Porta M, Servello D, Visser‐Vandewalle V, Silburn PA, Foltynie T, Walker HC, Shahed‐Jimenez J, Savica R, Klassen BT, Machado AG, Foote KD, Zhang J, Hu W, Ackermans L, Temel Y, Mari Z, Changizi BK, Lozano A, Auyeung M, Kaido T, Agid Y, Welter ML, Khandhar SM, Mogilner AY, Pourfar MH, Walter BL, Juncos JL, Gross RE, Kuhn J, Leckman JF, Neimat JA, Okun MS, Group T. Tourette syndrome deep brain stimulation: A review and updated recommendations. Movement Disorders 2014, 30: 448-471. PMID: 25476818, DOI: 10.1002/mds.26094.Peer-Reviewed Original ResearchConceptsDeep brain stimulationTourette syndromeBrain stimulationBehavioral treatment trialsFifth Edition diagnosisPostoperative outcome measuresOptimal surgical approachMultidisciplinary team approachTourette syndrome patientsMultiple brain targetsYears of ageLocal ethics committeeInstitutional review boardDBS centersMedication refractoryUrgent indicationsSevere motorSurgical approachTreatment trialsBrain targetsEdition diagnosisVocal ticsSyndrome patientsOutcome measuresHigh risk
2002
An Animal Model of Tourettes Syndrome
Taylor JR, Morshed SA, Parveen S, Mercadante MT, Scahill L, Peterson BS, King RA, Leckman JF, Lombroso PJ. An Animal Model of Tourettes Syndrome. American Journal Of Psychiatry 2002, 159: 657-660. PMID: 11925307, DOI: 10.1176/appi.ajp.159.4.657.Peer-Reviewed Original Research
1997
FUTURE THERAPIES OF TOURETTE SYNDROME * *Portions of this article have previously appeared in Chappell PB, Leckman JF, Riddle MA: The pharmacologic treatment of tic disorders. Child Adolesc Psychiatr Clin North Am. 4:197, 1995.
Chappell PB, Scahill LD, Leckman JF. FUTURE THERAPIES OF TOURETTE SYNDROME * *Portions of this article have previously appeared in Chappell PB, Leckman JF, Riddle MA: The pharmacologic treatment of tic disorders. Child Adolesc Psychiatr Clin North Am. 4:197, 1995. Neurologic Clinics 1997, 15: 429-450. PMID: 9115473, DOI: 10.1016/s0733-8619(05)70324-8.Peer-Reviewed Original ResearchConceptsTourette syndromeNew atypical antipsychotic medicationsCorticotropin-releasing factor antagonistAmino acid neurotransmitter systemsUnacceptable side effect profileAvailable pharmacologic therapiesNewer atypical antipsychoticsTreatment of ticsSide effect profileSubgroup of patientsAtypical antipsychotic medicationsTourette syndrome patientsLong-term courseReceptor affinity profileNonpharmacologic interventionsPharmacologic therapyPharmacologic treatmentAtypical antipsychoticsEffect profileAntipsychotic medicationTic disordersNeurotransmitter systemsSyndrome patientsFactor antagonistsSet of symptoms
1993
Reduced basal ganglia volumes in Tourette's syndrome using three-dimensional reconstruction techniques from magnetic resonance images.
Peterson B, Riddle MA, Cohen DJ, Katz LD, Smith JC, Hardin MT, Leckman JF. Reduced basal ganglia volumes in Tourette's syndrome using three-dimensional reconstruction techniques from magnetic resonance images. Neurology 1993, 43: 941-9. PMID: 8492950, DOI: 10.1212/wnl.43.5.941.Peer-Reviewed Original ResearchConceptsBasal gangliaSyndrome patientsNormal controlsReduced basal ganglia volumeBasal ganglia volumesTourette syndrome patientsGlobus pallidus nucleusSmaller mean volumesPathogenesis of TSEsNeuroleptic exposureGanglia volumesPallidus nucleusNeuroradiologic studiesTourette syndromeVolumetric asymmetryMean volumeMagnetic resonance imagesGangliaAxial imagesSocioeconomic statusAsymmetry indexSyndromeResonance imagesVolume reductionMR scanner