Assessment or central dopaminergic function using plasma-free homovanillic acid after debrisoquin administration
Riddle MA, Leckman JF, Cohen DJ, Anderson M, Ort SI, Caruso KA, Shaywitz BA. Assessment or central dopaminergic function using plasma-free homovanillic acid after debrisoquin administration. Journal Of Neural Transmission 1986, 67: 31-43. PMID: 3465864, DOI: 10.1007/bf01243357.Peer-Reviewed Original ResearchConceptsCentral dopaminergic functionDopaminergic functionHomovanillic acidDopamine metabolite homovanillic acidCentral DA activityChronic oral administrationPlasma-free homovanillic acidSingle oral doseBlood-brain barrierMetabolite homovanillic acidBehavioral side effectsOral dosePeripheral metabolismDA activityOral administrationSide effectsDebrisoquinAdministration methodsMarked reductionHVAAdministrationPeripheral formationAdultsValid techniqueChildren