2022
Mental Health Burden in Enlisted and Commissioned U.S. Military Veterans: Importance of Indirect Trauma Exposure in Commissioned Veterans
Merians AN, Na PJ, Tsai J, Harpaz-Rotem I, Pietrzak RH. Mental Health Burden in Enlisted and Commissioned U.S. Military Veterans: Importance of Indirect Trauma Exposure in Commissioned Veterans. Psychiatry 2022, 85: 418-432. PMID: 35532217, DOI: 10.1080/00332747.2022.2068301.Peer-Reviewed Original ResearchMeSH KeywordsDepressive Disorder, MajorHumansMental HealthStress Disorders, Post-TraumaticSubstance-Related DisordersSuicidal IdeationVeteransConceptsPosttraumatic stress disorderMajor depressive disorderU.S. military veteransSuicidal ideationMilitary veteransTrauma exposureMost mental health outcomesMental health burdenPast-year suicidal ideationDrug use disordersU.S. veteran populationMental health historyHigh exposureMental health outcomesMultivariable analysisDepressive disorderNational HealthHealth burdenPost-stratification weightsUse disordersVeteran populationHealth historyHealth outcomesIndirect trauma exposureVeterans Study
2019
Adoption by VA Residential Programs of Two Evidence-Based Psychotherapies for PTSD: Effect on Patient Outcomes
Cook JM, Schnurr PP, Simiola V, Thompson R, Hoff R, Harpaz-Rotem I. Adoption by VA Residential Programs of Two Evidence-Based Psychotherapies for PTSD: Effect on Patient Outcomes. Psychiatric Services 2019, 70: 553-560. PMID: 30966944, PMCID: PMC6690369, DOI: 10.1176/appi.ps.201800338.Peer-Reviewed Original ResearchMeSH KeywordsAdultCognitive Behavioral TherapyComorbidityDepressionFemaleHumansImplosive TherapyMaleMiddle AgedOutcome and Process Assessment, Health CarePsychological DistressResidential TreatmentStress Disorders, Post-TraumaticSubstance-Related DisordersUnited StatesUnited States Department of Veterans AffairsVeteransConceptsPosttraumatic stress disorderCognitive processing therapyEvidence-based psychotherapiesVeterans Affairs residential treatment programsAdoption groupsAlcohol useResidential treatment programSample of veteransGroup × time interactionPTSD symptomsStress disorderGroup formatProgram intakeResidential programs× time interactionDepression symptomsTreatment programPsychotherapyBasis of responsesPatient outcomesTime interactionProgram dischargeQualitative interviewsMonths postdischargeVeterans
2018
Latent typologies of DSM-5 PTSD symptoms in U.S. military veterans
Byrne SP, Harpaz-Rotem I, Tsai J, Southwick SM, Pietrzak RH. Latent typologies of DSM-5 PTSD symptoms in U.S. military veterans. Psychiatry Research 2018, 273: 266-273. PMID: 30658212, DOI: 10.1016/j.psychres.2018.12.094.Peer-Reviewed Original ResearchConceptsHigh symptom classPosttraumatic stress disorderSymptom classUse disordersLifetime historyDSM-5 PTSD symptomsPTSD symptomsLatent class analysisDrug use disordersNicotine use disorderDSM-5 posttraumatic stress disorderDSM-5 criteriaU.S. military veteransMajor depressiveCognitive impairmentU.S. veteransSymptomsPersonalized approachHigher symptomsStress disorderGeneralized anxietyMilitary veteransThree-class solutionDisordersVeterans
2017
Mental and Physical Health Conditions in US Combat Veterans: Results From the National Health and Resilience in Veterans Study.
Thomas MM, Harpaz-Rotem I, Tsai J, Southwick SM, Pietrzak RH. Mental and Physical Health Conditions in US Combat Veterans: Results From the National Health and Resilience in Veterans Study. The Primary Care Companion For CNS Disorders 2017, 19 PMID: 28657698, DOI: 10.4088/pcc.17m02118.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge FactorsCardiovascular DiseasesCross-Sectional StudiesFemaleHealth StatusHumansMaleMental DisordersMental HealthMiddle AgedMigraine DisordersResilience, PsychologicalSex FactorsSocioeconomic FactorsSubstance-Related DisordersSuicideUnited StatesVeteransWar ExposureYoung AdultConceptsPhysical health conditionsPosttraumatic stress disorderOlder combat veteransCurrent posttraumatic stress disorderGreater oddsHealth conditionsChronic painHeart diseaseUS veteransNational HealthMigraine headacheCombat veteransSuicidal ideationVeterans StudyCurrent generalized anxiety disorderHeart attackVeterans Affairs Healthcare SystemLifetime posttraumatic stress disorderUS veteran populationElevated ratesPopulation-based burdenCurrent psychiatric disorderDrug use disordersMental health factorsGeneralized anxiety disorderOne-Year Incidence and Predictors of Homelessness Among 300,000 U.S. Veterans Seen in Specialty Mental Health Care
Tsai J, Hoff RA, Harpaz-Rotem I. One-Year Incidence and Predictors of Homelessness Among 300,000 U.S. Veterans Seen in Specialty Mental Health Care. Psychological Services 2017, 14: 203-207. PMID: 28481605, DOI: 10.1037/ser0000083.Peer-Reviewed Original ResearchConceptsSpecialty mental health clinicsMental health clinicsHealth clinicsRetrospective cohort study designVeterans AffairsSpecialty mental health careCohort study designVA medical recordsDrug use disordersMental health careVA homeless servicesClinical predictorsProspective studyMedical recordsDisorders ClinicInternational ClassificationUse disordersVA facilitiesU.S. veteransEarly signsStudy designVA effortsClinicHealth careIncidence
2016
FKBP5 polymorphisms, childhood abuse, and PTSD symptoms: Results from the National Health and Resilience in Veterans Study
Watkins LE, Han S, Harpaz-Rotem I, Mota NP, Southwick SM, Krystal JH, Gelernter J, Pietrzak RH. FKBP5 polymorphisms, childhood abuse, and PTSD symptoms: Results from the National Health and Resilience in Veterans Study. Psychoneuroendocrinology 2016, 69: 98-105. PMID: 27078785, DOI: 10.1016/j.psyneuen.2016.04.001.Peer-Reviewed Original ResearchAdultAllelesChildChild AbuseGene-Environment InteractionGenetic Predisposition to DiseaseGenotypeHumansHypothalamo-Hypophyseal SystemLinkage DisequilibriumMalePituitary-Adrenal SystemPolymorphism, Single NucleotideRisk FactorsStress Disorders, Post-TraumaticSubstance-Related DisordersTacrolimus Binding ProteinsVeteransNature and determinants of suicidal ideation among U.S. veterans: Results from the national health and resilience in veterans study
Smith NB, Mota N, Tsai J, Monteith L, Harpaz-Rotem I, Southwick SM, Pietrzak RH. Nature and determinants of suicidal ideation among U.S. veterans: Results from the national health and resilience in veterans study. Journal Of Affective Disorders 2016, 197: 66-73. PMID: 26970267, DOI: 10.1016/j.jad.2016.02.069.Peer-Reviewed Original ResearchConceptsChronic suicidal ideationPhysical health difficultiesSuicidal ideationU.S. veteransProtective psychosocial characteristicsNational HealthPsychosocial characteristicsHealth difficultiesSI onsetMajor public health concernProspective cohort studyPublic health concernSubstance abuse historyWave 1Majority of veteransU.S. military veteransCohort studyProtective correlatesTwo-week timeframePsychiatric distressVeterans StudySociodemographic characteristicsSuicidal thoughtsHealth concernTreatment efforts
2013
Latent class analysis of personality disorders in adults with posttraumatic stress disorder: results from the National Epidemiologic Survey on Alcohol and Related Conditions.
Tsai J, Harpaz-Rotem I, Pilver CE, Wolf EJ, Hoff RA, Levy KN, Sareen J, Pietrzak RH. Latent class analysis of personality disorders in adults with posttraumatic stress disorder: results from the National Epidemiologic Survey on Alcohol and Related Conditions. The Journal Of Clinical Psychiatry 2013, 75: 276-84. PMID: 24345427, DOI: 10.4088/jcp.13m08466.Peer-Reviewed Original ResearchConceptsHealth-related qualityMental health-related qualityPosttraumatic stress disorderDSM-IV personality disordersNational Epidemiologic SurveyPersonality disorderDisorder classesEpidemiologic SurveyLower mental health-related qualityRelated conditionsComorbid Axis I disordersStress disorderTreatment of PTSDPTSD symptomsComorbid Axis I diagnosesAxis I comorbidityLatent class analysisCo-occurring personality disordersAxis I diagnosisAxis I DisordersTreatment characteristicsI disordersUS adultsLifetime diagnosisTreatment approachesPredominant typologies of psychopathology in the United States: A latent class analysis
El-Gabalawy R, Tsai J, Harpaz-Rotem I, Hoff R, Sareen J, Pietrzak RH. Predominant typologies of psychopathology in the United States: A latent class analysis. Journal Of Psychiatric Research 2013, 47: 1649-1657. PMID: 23978394, DOI: 10.1016/j.jpsychires.2013.07.028.Peer-Reviewed Original ResearchConceptsPopulation-based sampleSubstance use disordersAxis IU.S. adultsLatent class analysisUse disordersSuicide attemptsMental health-related qualityHealth-related qualityLifetime psychiatric disordersRates of moodAxis II disordersNational Epidemiologic SurveyPsychiatric comorbidityOverall high ratePsychiatric disordersEpidemiologic SurveyComorbid classesMental disordersClass analysisRelated conditionsAnxiety disordersBorderline/Personality disorderDisorders
2012
Health and Social Adjustment of Homeless Older Adults With a Mental Illness
Gordon RJ, Rosenheck RA, Zweig RA, Harpaz-Rotem I. Health and Social Adjustment of Homeless Older Adults With a Mental Illness. Psychiatric Services 2012, 63: 561-568. PMID: 22476721, DOI: 10.1176/appi.ps.201100175.Peer-Reviewed Original ResearchMeSH KeywordsAdultAge FactorsAgedCase ManagementFemaleFollow-Up StudiesHousingHumansIll-Housed PersonsMaleMental DisordersMiddle AgedSocial AdjustmentSocial SupportSubstance-Related DisordersConceptsOlder homeless adultsPsychiatric symptomsMental illnessSubstance useOlder adultsHomeless adultsIntensive case management servicesMental healthYoung adultsSevere mental healthGeneral medical healthCase management servicesChi-square testSocial supportSubstance abuse problemsMixed-model analysisTreatment strategiesCommunity careThree monthsAge groupsSquare testYounger groupSpecific interventionsYounger counterpartsPhysical health
2011
Residential treatment for homeless female veterans with psychiatric and substance use disorders: Effect on 1-year clinical outcomes
Harpaz-Rotem I, Rosenheck RA, Desai R. Residential treatment for homeless female veterans with psychiatric and substance use disorders: Effect on 1-year clinical outcomes. The Journal Of Rehabilitation Research And Development 2011, 48: 891. PMID: 22068368, DOI: 10.1682/jrrd.2010.10.0195.Peer-Reviewed Original ResearchMeSH KeywordsAdultDiagnosis, Dual (Psychiatry)EmploymentFemaleFollow-Up StudiesHousingHumansIll-Housed PersonsLength of StayMental DisordersMiddle AgedRecurrenceResidential TreatmentSocial SupportSubstance-Related DisordersTime FactorsTreatment OutcomeUnited StatesUnited States Department of Veterans AffairsVeteransConceptsClinical outcomesResidential treatmentHomeless female veteransPsychiatric symptomsFemale veteransSerious mental illnessSubstance use disordersUse of drugsGroup of veteransMental health outcomesNRT groupRT groupPsychiatric problemsUse disordersBetter outcomesHealth outcomesMental illnessHomeless womenVeterans AffairsAlcohol useBeneficial effectsLimited evidenceSubstance useOutcomesProgram entry
2009
Seeking safety therapy: clarification of results.
Desai RA, Harpaz-Rotem I, Najavits LM, Rosenheck RA. Seeking safety therapy: clarification of results. Psychiatric Services 2009, 60: 125. PMID: 19114585.Peer-Reviewed Original Research
2008
Impact of the Seeking Safety Program on Clinical Outcomes Among Homeless Female Veterans With Psychiatric Disorders
Desai RA, Harpaz-Rotem I, Najavits LM, Rosenheck RA. Impact of the Seeking Safety Program on Clinical Outcomes Among Homeless Female Veterans With Psychiatric Disorders. Psychiatric Services 2008, 59: 996-1003. PMID: 18757592, DOI: 10.1176/ps.2008.59.9.996.Peer-Reviewed Original ResearchMeSH KeywordsAdultCase ManagementCognitive Behavioral TherapyCohort StudiesComorbidityFemaleFollow-Up StudiesHumansIll-Housed PersonsInterpersonal RelationsMaleMental DisordersMiddle AgedOutcome and Process Assessment, Health CareSafetySecondary PreventionSocial AdjustmentSocial SupportStress Disorders, Post-TraumaticSubstance-Related DisordersVeteransConceptsClinical outcomesSeeking SafetyHomeless women veteransSafety cohortHomeless female veteransWomen veteransFemale veteransMost clinical outcome measuresOne-year clinical outcomesVeterans Affairs Medical CenterClinical outcome measuresComorbid substance abuseIntensive case managementCognitive behavioral therapy interventionVeteran ProgramPosttraumatic stress disorderSubstance abuse problemsPostimplementation cohortGeneral symptomsLower followOutcome measuresMedical CenterPsychiatric disordersTherapy interventionArousal clusters