2019
Neural computations of threat in the aftermath of combat trauma
Homan P, Levy I, Feltham E, Gordon C, Hu J, Li J, Pietrzak RH, Southwick S, Krystal JH, Harpaz-Rotem I, Schiller D. Neural computations of threat in the aftermath of combat trauma. Nature Neuroscience 2019, 22: 470-476. PMID: 30664770, PMCID: PMC6829910, DOI: 10.1038/s41593-018-0315-x.Peer-Reviewed Original ResearchConceptsPTSD symptomsPost-traumatic stress disorder symptomsHigher PTSD symptom severityThreat-predictive cuesPTSD symptom severityAssociative threatPredictive cuesNeural trackingDisorder symptomsPrediction errorCombat veteransDynamic learning rateNegative outcomesCombat traumaSmaller amygdala volumesNeural computationLatent markersSymptomatic veteransSymptom severityAmygdala volumeAssociabilityCuesLearning rateVeteransSymptoms
2014
Determinants of Prospective Engagement in Mental Health Treatment Among Symptomatic Iraq/Afghanistan Veterans
Harpaz-Rotem I, Rosenheck RA, Pietrzak RH, Southwick SM. Determinants of Prospective Engagement in Mental Health Treatment Among Symptomatic Iraq/Afghanistan Veterans. The Journal Of Nervous And Mental Disease 2014, 202: 97-104. PMID: 24469520, DOI: 10.1097/nmd.0000000000000078.Peer-Reviewed Original ResearchConceptsMental health treatmentPosttraumatic stress disorderIraq/Afghanistan veteransHealth treatmentAfghanistan veteransSymptomatic veteransMental health visitsMental health screeningMental health statusMental health servicesHealth visitsHealth screeningService utilizationRe-experiencing symptomsDepressive symptomsHealth statusHealth servicesPsychosocial determinantsStress disorderSymptomsVeteransTreatmentConsistent determinantsNumbing symptomsProspective engagement
2012
Examining the relation between combat-related concussion, a novel 5-factor model of posttraumatic stress symptoms, and health-related quality of life in Iraq and Afghanistan veterans.
Tsai J, Whealin JM, Scott JC, Harpaz-Rotem I, Pietrzak RH. Examining the relation between combat-related concussion, a novel 5-factor model of posttraumatic stress symptoms, and health-related quality of life in Iraq and Afghanistan veterans. The Journal Of Clinical Psychiatry 2012, 73: 1110-8. PMID: 22781019, DOI: 10.4088/jcp.11m07587.Peer-Reviewed Original ResearchConceptsMental health-related qualityHealth-related qualityPersistent postconcussive symptomsCombat-related concussionPostconcussive symptomsAlcohol use problemsPTSD symptomsAfghanistan veteransPhysical health-related qualityForm Health SurveyDysphoric arousal symptomsUse problemsIraq/Afghanistan veteransStrongest predictorPosttraumatic stress disorder (PTSD) symptomsClinical characteristicsProgram registryHealth SurveyPsychiatric cliniciansPosttraumatic stress symptomsMultivariate analysisSymptomsConcussionBivariate analysisSymptomatic veterans