2021
The self in context: brain systems linking mental and physical health
Koban L, Gianaros PJ, Kober H, Wager TD. The self in context: brain systems linking mental and physical health. Nature Reviews Neuroscience 2021, 22: 309-322. PMID: 33790441, PMCID: PMC8447265, DOI: 10.1038/s41583-021-00446-8.Peer-Reviewed Original ResearchMeSH KeywordsBrainBrain MappingEgoHealth StatusHumansMagnetic Resonance ImagingMental HealthNerve NetPrefrontal CortexConceptsVentromedial prefrontal cortexDefault mode networkPhysical healthPrefrontal cortexHigh-level cognitionCause of experienceBrain systemsSomatic physiologySensory modalitiesNeural systemsPersonal meaningPeripheral physiologyMental healthFormation of narrativesConvergent alterationsSelfContext modelCortexImmune functionCognitionExperienceContextHealthBeliefsMindset
2019
Let it be: mindful acceptance down-regulates pain and negative emotion
Kober H, Buhle J, Weber J, Ochsner KN, Wager TD. Let it be: mindful acceptance down-regulates pain and negative emotion. Social Cognitive And Affective Neuroscience 2019, 14: 1147-1158. PMID: 31989171, PMCID: PMC7057281, DOI: 10.1093/scan/nsz104.Peer-Reviewed Original ResearchMeSH KeywordsAdultAmygdalaBrainBrain MappingDepressionEmotionsFemaleHumansMaleMeditationMindfulnessPainPain ManagementYoung AdultConceptsMindful acceptanceEmotion regulation strategiesCognitive control systemPrefrontal control systemsMeditation-naïve participantsSelf-report measuresKinds of stimuliEmotion regulationNeutral imagesNegative emotionsAmygdala responseMindfulness trainingNegative affectAffective significanceEmotional intensityRegulation strategiesBrain processesNegative imageInitial appraisalEmotionsLateral pain systemPain systemStimuliParticipantsChronic pain
2016
Neural stress reactivity relates to smoking outcomes and differentiates between mindfulness and cognitive-behavioral treatments
Kober H, Brewer JA, Height KL, Sinha R. Neural stress reactivity relates to smoking outcomes and differentiates between mindfulness and cognitive-behavioral treatments. NeuroImage 2016, 151: 4-13. PMID: 27693614, PMCID: PMC5373945, DOI: 10.1016/j.neuroimage.2016.09.042.Peer-Reviewed Original ResearchConceptsCognitive-behavioral treatmentFunctional magnetic resonance imagingStress reactivityMindfulness-based treatmentsAmerican Lung Association's FreedomUnderstanding of stressPsychological mechanismsMindfulness trainingNegative affectConjunction analysisMid insulaCBT groupStress provocationSmoking outcomesBrain regionsCessation treatmentEfficacy of MTCurrent studyEntire sampleDrug useSmoking cessationImportant implicationsMagnetic resonance imagingMindfulnessInsula
2013
Cognitive Reappraisal of Emotion: A Meta-Analysis of Human Neuroimaging Studies
Buhle JT, Silvers JA, Wager TD, Lopez R, Onyemekwu C, Kober H, Weber J, Ochsner KN. Cognitive Reappraisal of Emotion: A Meta-Analysis of Human Neuroimaging Studies. Cerebral Cortex 2013, 24: 2981-2990. PMID: 23765157, PMCID: PMC4193464, DOI: 10.1093/cercor/bht154.Peer-Reviewed Original ResearchConceptsLateral temporal cortexCognitive reappraisalEmotional respondingTemporal cortexSemantic representationEmotion regulation strategiesCognitive control regionsParietal control regionsVentromedial prefrontal cortexHuman neuroimaging studiesEmotion-related responsesCognitive controlEmotional stimuliFear extinctionAmygdala responseNegative affectRegulation strategiesNeuroimaging studiesBilateral amygdalaPrefrontal cortexAffective impactBrain regionsAttenuate activityAmygdalaReappraisal
2011
Meditation experience is associated with differences in default mode network activity and connectivity
Brewer JA, Worhunsky PD, Gray JR, Tang YY, Weber J, Kober H. Meditation experience is associated with differences in default mode network activity and connectivity. Proceedings Of The National Academy Of Sciences Of The United States Of America 2011, 108: 20254-20259. PMID: 22114193, PMCID: PMC3250176, DOI: 10.1073/pnas.1112029108.Peer-Reviewed Original ResearchMeSH KeywordsBrain MappingGyrus CinguliHumansLinear ModelsMeditationNerve NetPrefrontal CortexSelf ReportTemporal LobeConceptsDefault mode networkExperienced meditatorsDefault mode network activitySelf-referential processingDorsal anterior cingulateDorsolateral prefrontal cortexPossible neural mechanismsFunctional connectivity analysisMeditation typesNeural mechanismsMeditation experienceBrain activityDefault modePrefrontal cortexAnterior cingulatePosterior cingulateContemplative traditionsConnectivity analysisDifferent meditations
2010
Prefrontal–striatal pathway underlies cognitive regulation of craving
Kober H, Mende-Siedlecki P, Kross EF, Weber J, Mischel W, Hart CL, Ochsner KN. Prefrontal–striatal pathway underlies cognitive regulation of craving. Proceedings Of The National Academy Of Sciences Of The United States Of America 2010, 107: 14811-14816. PMID: 20679212, PMCID: PMC2930456, DOI: 10.1073/pnas.1007779107.Peer-Reviewed Original ResearchConceptsSubstance use disordersUse disordersPrefrontal cortexVentral tegmental areaSubstance-dependent populationsMore effective treatmentsLong-term consumptionDorsolateral prefrontal cortex activityPrefrontal cortex activityCigarette smokersTegmental areaVentrolateral prefrontal cortexVentral striatum activityVentral striatal activitySubgenual cingulateEffective treatmentLateral prefrontal cortexStriatal activityVentral striatumCortex activityFunctional imagingPhysical healthStriatum activityNeural activityCortex
2008
Functional grouping and cortical–subcortical interactions in emotion: A meta-analysis of neuroimaging studies
Kober H, Barrett LF, Joseph J, Bliss-Moreau E, Lindquist K, Wager TD. Functional grouping and cortical–subcortical interactions in emotion: A meta-analysis of neuroimaging studies. NeuroImage 2008, 42: 998-1031. PMID: 18579414, PMCID: PMC2752702, DOI: 10.1016/j.neuroimage.2008.03.059.Peer-Reviewed Original ResearchMeSH KeywordsBrain MappingCerebral CortexDiagnostic ImagingEmotionsHumansNerve NetNeural PathwaysNeuroanatomyConceptsBrain regionsFrontal cortexCore limbic structuresFrontal cortical areasCo-activated brain regionsMedial frontal areasLateral frontal cortexBrainstem groupPeriaqueductal grayLimbic structuresHypothalamic activationLimbic activationDorsomedial prefrontal cortexCortical-subcortical interactionsCortical areasSubcortical activationCortical groupSpecific followVentral striatumFrontal groupPrefrontal cortexCortexAnimal literatureCognitive generationConsistent activation