2000
Rate of caudate atrophy in presymptomatic and symptomatic stages of Huntington's disease
Aylward E, Codori A, Rosenblatt A, Sherr M, Brandt J, Stine O, Barta P, Pearlson G, Ross C. Rate of caudate atrophy in presymptomatic and symptomatic stages of Huntington's disease. Movement Disorders 2000, 15: 552-560. PMID: 10830423, DOI: 10.1002/1531-8257(200005)15:3<552::aid-mds1020>3.0.co;2-p.Peer-Reviewed Original ResearchConceptsUseful outcome measureCaudate volumeHuntington's diseaseSymptomatic patientsSymptomatic subjectsCaudate atrophyOutcome measuresLongitudinal changesStages of HDMean interscan intervalSerial magnetic resonance imagesHD gene mutationNeurological examSymptomatic groupModerate symptomsMild symptomsSymptomatic stagePresymptomatic carriersTherapeutic studiesTreatment effectivenessPatientsMagnetic resonance imagesDiseaseGene mutationsInterscan interval
1986
STRUCTURAL BRAIN CORRELATES OF EMOTIONAL DISORDER IN MULTIPLE SCLEROSIS
RABINS P, BROOKS B, O'DONNELL P, PEARLSON G, MOBERG P, JUBELT B, COYLE P, DALOS N, FOLSTEIN M. STRUCTURAL BRAIN CORRELATES OF EMOTIONAL DISORDER IN MULTIPLE SCLEROSIS. Brain 1986, 109: 585-597. PMID: 3730806, DOI: 10.1093/brain/109.4.585.Peer-Reviewed Original ResearchConceptsStable spinal cord injuriesMini-Mental State ExaminationMultiple sclerosisBrain involvementSCI patientsMS patientsDepression scoresMean General Health Questionnaire scoresProgressive multiple sclerosisDefinite multiple sclerosisGeneral Health Questionnaire scoresSpinal cord injuryMean depression scoreStructural brain correlatesCord lesionsFunctional disabilityCord injuryNeurological impairmentCT scanQuestionnaire scoresPatientsState ExaminationCognitive disordersAbnormal rangeOne-year study