2009
Functional and Structural Connectivity Between the Perigenual Anterior Cingulate and Amygdala in Bipolar Disorder
Wang F, Kalmar JH, He Y, Jackowski M, Chepenik LG, Edmiston E, Tie K, Gong G, Shah MP, Jones M, Uderman J, Constable RT, Blumberg HP. Functional and Structural Connectivity Between the Perigenual Anterior Cingulate and Amygdala in Bipolar Disorder. Biological Psychiatry 2009, 66: 516-521. PMID: 19427632, PMCID: PMC2830492, DOI: 10.1016/j.biopsych.2009.03.023.Peer-Reviewed Original ResearchConceptsPerigenual anterior cingulate cortexHealthy comparison subjectsBipolar disorderFunctional magnetic resonance imagingDiffusion tensor imagingFunctional connectivityWhite matterFractional anisotropyHC groupPerigenual anterior cingulateAnterior cingulate cortexMagnetic resonance imagingGray matter structuresRegional fractional anisotropyWhite matter connectivityEmotional processingFunctional connectivity measuresSignificant positive associationBD groupComparison subjectsAnterior cingulateCingulate cortexResonance imagingSignificant associationBrain regions
2008
Abnormal anterior cingulum integrity in bipolar disorder determined through diffusion tensor imaging
Wang F, Jackowski M, Kalmar JH, Chepenik LG, Tie K, Qiu M, Gong G, Pittman BP, Jones MM, Shah MP, Spencer L, Papademetris X, Constable RT, Blumberg HP. Abnormal anterior cingulum integrity in bipolar disorder determined through diffusion tensor imaging. The British Journal Of Psychiatry 2008, 193: 126-129. PMID: 18669996, PMCID: PMC2732002, DOI: 10.1192/bjp.bp.107.048793.Peer-Reviewed Original ResearchConceptsBipolar disorderWhite matter connectionsFractional anisotropyAnterior cingulumPosterior cingulumAbnormal white matter integrityWhite matter abnormalitiesBipolar disorder groupAnterior cingulate cortexDiffusion tensorWhite matter integrityHealthy groupCingulate cortexNeural systemsHealthy participantsDisorder groupDisordersAbnormalitiesCingulumConvergent evidenceGroupParticipantsEmotional regulation