Complete deletion of the androgen receptor gene: definition of the null phenotype of the androgen insensitivity syndrome and determination of carrier status
Quigley C, Friedman K, Johnson A, Lafreniere R, Silverman L, Lubahn D, Brown T, Wilson E, Willard H, French F. Complete deletion of the androgen receptor gene: definition of the null phenotype of the androgen insensitivity syndrome and determination of carrier status. The Journal Of Clinical Endocrinology & Metabolism 1992, 74: 927-933. DOI: 10.1210/jc.74.4.927.Peer-Reviewed Original ResearchAR geneNull phenotypeCDNA probeSouthern blot analysis of genomic DNADensitometric analysis of Southern blotsAnalysis of Southern blotsDetermination of carrier statusAnalysis of genomic DNAX-linked DNA polymorphismsAndrogen insensitivityControl cDNA probesHindIII restriction fragment length polymorphismGene dosage studiesCarrier statusRestriction fragment length polymorphismSouthern blot analysisFragment length polymorphismComplete androgen insensitivityPolymerase chain reaction amplificationAndrogen insensitivity syndromePattern of inheritanceAndrogen receptorUnrelated genesDNA polymorphismsOriginal mutation