2022
D3 Receptors and PET Imaging
Koohsari S, Yang Y, Matuskey D. D3 Receptors and PET Imaging. Current Topics In Behavioral Neurosciences 2022, 60: 251-275. PMID: 35711027, DOI: 10.1007/7854_2022_374.Peer-Reviewed Original Research
2018
Positron emission tomography imaging of the γ-aminobutyric acid system
Andersson JD, Matuskey D, Finnema SJ. Positron emission tomography imaging of the γ-aminobutyric acid system. Neuroscience Letters 2018, 691: 35-43. PMID: 30102960, DOI: 10.1016/j.neulet.2018.08.010.Peer-Reviewed Original ResearchConceptsPositron emission tomographyGABA levelsΓ-aminobutyric acid A (GABAA) receptorsGABA sensitivityEmission tomographyImportance of GABACentral nervous systemAminobutyric acid systemBenzodiazepine binding siteEndogenous GABA levelsGABA releaseGABA transmissionGABA systemNervous systemGABA concentrationPET tracersPET imagingAgonist GABAA receptorsBasic physiologyGABARadioligandReceptorsTomographyTranslational applications
2014
Dopamine D3 receptor alterations in cocaine-dependent humans imaged with [11C](+)PHNO
Matuskey D, Gallezot JD, Pittman B, Williams W, Wanyiri J, Gaiser E, Lee DE, Hannestad J, Lim K, Zheng MQ, Lin SF, Labaree D, Potenza MN, Carson RE, Malison RT, Ding YS. Dopamine D3 receptor alterations in cocaine-dependent humans imaged with [11C](+)PHNO. Drug And Alcohol Dependence 2014, 139: 100-105. PMID: 24717909, PMCID: PMC4071607, DOI: 10.1016/j.drugalcdep.2014.03.013.Peer-Reviewed Original ResearchConceptsCocaine dependenceCD subjectsIllicit substance abuseHealthy control subjectsCocaine-dependent humansGroup differencesHistory of cocaineReference tissue modelDopaminergic transmissionReceptor alterationsSubstantia nigraControl subjectsAnimal modelsReceptor availabilityEarly abstinenceCocaine useSubstance abuseBPND valuesAvailable receptorsPilot studyAmygdalaReference regionPallidumReceptorsPotential relevance