2020
Resting state hypothalamic and dorsomedial prefrontal cortical connectivity of the periaqueductal gray in cocaine addiction
Zhang S, Zhornitsky S, Wang W, Le TM, Dhingra I, Chen Y, Li C. Resting state hypothalamic and dorsomedial prefrontal cortical connectivity of the periaqueductal gray in cocaine addiction. Addiction Biology 2020, 26: e12989. PMID: 33300238, PMCID: PMC8614224, DOI: 10.1111/adb.12989.Peer-Reviewed Original ResearchConceptsPeriaqueductal grayPain circuitsDrug useCocaine addictionFunctional connectivityPrefrontal cortical connectivityState functional connectivityReward circuit dysfunctionRecent cocaine useHealthy control participantsInferior parietal cortexCompulsive drug useHabitual drug useCircuit dysfunctionCocaine withdrawalCocaine-dependent individualsCocaine cravingCortical connectivitySignificant anxietyDorsomedial prefrontalParietal cortexCocaine useIntrinsic connectivitySubcortical hubsDrug seekingNeural responses to negative facial emotions: Sex differences in the correlates of individual anger and fear traits
Li G, Zhang S, Le TM, Tang X, Li CR. Neural responses to negative facial emotions: Sex differences in the correlates of individual anger and fear traits. NeuroImage 2020, 221: 117171. PMID: 32682098, PMCID: PMC7789231, DOI: 10.1016/j.neuroimage.2020.117171.Peer-Reviewed Original ResearchConceptsNegative facial emotionsFacial emotionsMiddle frontal cortexShape targetRetrosplenial cortexEmotion processingIndividual differencesProlonged RTHigher activationRight middle frontal cortexLeft retrosplenial cortexBilateral middle frontal cortexFrontal cortexSex-specific behavioralShape identificationHuman Connectome ProjectRegional brain responsesEmotion measuresAffective traitsNeural processesBrain responsesFear traitsNeural responsesEmotional disordersIndividuals' anger
2019
Hypothalamic Responses to Cocaine and Food Cues in Individuals with Cocaine Dependence
Zhang S, Zhornitsky S, Le TM, Li CR. Hypothalamic Responses to Cocaine and Food Cues in Individuals with Cocaine Dependence. The International Journal Of Neuropsychopharmacology 2019, 22: 754-764. PMID: 31420667, PMCID: PMC6929672, DOI: 10.1093/ijnp/pyz044.Peer-Reviewed Original ResearchConceptsHealthy control participantsHypothalamic activationCocaine useCocaine-dependent participantsFood cuesCocaine addictionHypothalamic responseControl participantsCocaine Craving QuestionnaireRecent cocaine useFunctional magnetic resonance imagingMagnetic resonance imagingCue-related activationsInferior parietal cortexHypothalamic dysfunctionClinical variablesDopaminergic pathwaysTonic cravingFood intakeQuestionnaire scoresRodent studiesVisual cortexParietal cortexResonance imagingHypothalamusImaging the effects of age on proactive control in healthy adults
Hu S, Job M, Jenks SK, Chao HH, Li CR. Imaging the effects of age on proactive control in healthy adults. Brain Imaging And Behavior 2019, 13: 1526-1537. PMID: 31011949, PMCID: PMC6812594, DOI: 10.1007/s11682-019-00103-w.Peer-Reviewed Original ResearchConceptsInferior occipital gyrusStop-signal reaction timePrefrontal cortexProactive controlProactive inhibitionOlder adultsReactive inhibitionSuperior parietal lobuleSequential effectsEffect of ageSignal reaction timeCaudate headDistinct neural processesParacentral lobuleTrial reaction timeVentromedial prefrontal cortexLateral prefrontal cortexHealthy adultsNeural changesNeural plasticityOccipital gyrusParietal lobuleReaction timeYoung adultsBelief ModelCerebral responses to self-initiated action during social interactions
Wang W, Zhornitsky S, Li C, Zhang S, Ide JS, Joormann J, Li CR. Cerebral responses to self-initiated action during social interactions. Cognitive, Affective, & Behavioral Neuroscience 2019, 19: 1521-1535. PMID: 30941709, PMCID: PMC6774916, DOI: 10.3758/s13415-019-00711-5.Peer-Reviewed Original ResearchConceptsSelf-initiated actionsSocial interactionSocial communication needsSocial behavioral disordersPosterior cortical activationSocial exclusionHealthy adultsMind processingCyberball gameSocial anxietySocial emotionsNeural correlatesPercentage of trialsSubjective awarenessAngular gyrusNeural markersCortical activationCortical activityBall tossBehavioral disordersCerebral responsesFuture researchCommunication needsExtant studiesOwn volition
2015
Altered resting‐state functional connectivity of the insula in young adults with Internet gaming disorder
Zhang JT, Yao YW, Li CS, Zang YF, Shen ZJ, Liu L, Wang LJ, Liu B, Fang XY. Altered resting‐state functional connectivity of the insula in young adults with Internet gaming disorder. Addiction Biology 2015, 21: 743-751. PMID: 25899520, PMCID: PMC4615265, DOI: 10.1111/adb.12247.Peer-Reviewed Original ResearchConceptsResting-state functional connectivityHealthy control subjectsSuperior temporal gyrusAnterior cingulate cortexPosterior insulaAnterior insulaStronger resting-state functional connectivityGender-matched healthy control subjectsMagnetic resonance imaging studyInternet gaming disorderAngular gyrusSupplemental motor areaResonance imaging studyFunctional magnetic resonance imaging studyClinical manifestationsControl subjectsFunctional abnormalitiesPostcentral gyrusMotor areaPrecentral gyrusCingulate cortexImaging studiesIGD subjectsTemporal gyrusCore symptomsCausal Interactions Within a Frontal-Cingulate-Parietal Network During Cognitive Control: Convergent Evidence from a Multisite–Multitask Investigation
Cai W, Chen T, Ryali S, Kochalka J, Li CS, Menon V. Causal Interactions Within a Frontal-Cingulate-Parietal Network During Cognitive Control: Convergent Evidence from a Multisite–Multitask Investigation. Cerebral Cortex 2015, 26: 2140-2153. PMID: 25778346, PMCID: PMC4830290, DOI: 10.1093/cercor/bhv046.Peer-Reviewed Original ResearchConceptsDorsal anterior cingulate cortexCognitive controlAnterior insulaParietal networkCausal interactionsCognitive control resourcesCognitive control abilitiesCognitive control processesCognitive control modelCognitive control taskGoal-directed behaviorAnterior cingulate cortexSignificant causal influenceBrain mechanismsIndividual differencesCausal outflowCingulate cortexFMRI dataControl taskCausal hubCausal influenceControl abilityControl processControl resourcesTask
2014
Functional Clustering of the Human Inferior Parietal Lobule by Whole-Brain Connectivity Mapping of Resting-State Functional Magnetic Resonance Imaging Signals
Zhang S, Li CS. Functional Clustering of the Human Inferior Parietal Lobule by Whole-Brain Connectivity Mapping of Resting-State Functional Magnetic Resonance Imaging Signals. Brain Connectivity 2014, 4: 53-69. PMID: 24308753, PMCID: PMC3929139, DOI: 10.1089/brain.2013.0191.Peer-Reviewed Original ResearchConceptsInferior parietal lobuleHuman inferior parietal lobuleParietal lobulePosterior inferior parietal lobuleFunctional magnetic resonance imaging (fMRI) dataResting-state functional magnetic resonance imaging (fMRI) dataInferior frontal gyrusFunctional magnetic resonance imaging (fMRI) signalsEarlier fMRI studiesDefault mode networkSpatial attentionCognitive challengesIntraparietal sulcusFMRI studyMathematical cognitionFrontal gyrusAngular gyrusSupramarginal gyrusHemispheric differencesMode networkMagnetic resonance imaging dataFunctional segregationRegional activationLanguage processingPosterior subregions
2011
Functional connectivity mapping of the human precuneus by resting state fMRI
Zhang S, Li CS. Functional connectivity mapping of the human precuneus by resting state fMRI. NeuroImage 2011, 59: 3548-3562. PMID: 22116037, PMCID: PMC3288461, DOI: 10.1016/j.neuroimage.2011.11.023.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultBrain MappingFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedParietal LobeRestYoung AdultConceptsVentral precuneusGreater connectivityDorsal precuneusFrontal gyrusSelf-related processingLess connectivityDorsal anteriorSuperior temporal gyrusMiddle frontal gyrusPosterior parietal cortexDefault mode networkMiddle occipital gyrusOrbital frontal gyrusAnterior cingulate gyrusHippocampus/parahippocampusMental imageryEpisodic memoryCognitive processesPosterior precuneusVisual imageryHuman precuneusFunctional neuroanatomyAngular gyrusTemporal gyrusNegative connectivity
2010
Association of Frontal and Posterior Cortical Gray Matter Volume With Time to Alcohol Relapse: A Prospective Study
Rando K, Hong KI, Bhagwagar Z, Li CS, Bergquist K, Guarnaccia J, Sinha R. Association of Frontal and Posterior Cortical Gray Matter Volume With Time to Alcohol Relapse: A Prospective Study. American Journal Of Psychiatry 2010, 168: 183-192. PMID: 21078704, PMCID: PMC3668974, DOI: 10.1176/appi.ajp.2010.10020233.Peer-Reviewed Original ResearchConceptsGray matter volume deficitsGray matter volumeAlcohol-dependent patientsMatter volumeVolume deficitsAlcohol relapseRelapse riskComparison subjectsBrain regionsCortical gray matter volumeAlcohol useRegional brain volume differencesSmaller gray matter volumePoor clinical outcomeBrain volume deficitsFrontal gray matter volumeGray matter atrophyAbstinent alcohol-dependent patientsAlcoholism treatment outcomeHigh-resolution structural MRIProspective study designHealthy comparison subjectsVoxel-based morphometryAlcohol-dependent groupMonths of abstinence
2009
A neural measure of behavioral engagement: Task-residual low-frequency blood oxygenation level-dependent activity in the precuneus
Zhang S, Li CS. A neural measure of behavioral engagement: Task-residual low-frequency blood oxygenation level-dependent activity in the precuneus. NeuroImage 2009, 49: 1911-1918. PMID: 19761851, PMCID: PMC2791356, DOI: 10.1016/j.neuroimage.2009.09.004.Peer-Reviewed Original ResearchConceptsBlood oxygenation level-dependent activityRegional brain activationLevel-dependent activityTask engagementNeural measuresNeural processesBrain activationPosterior cingulate cortexAttentional monitoringResponse inhibitionHuman cognitionPrefrontal activationSignal taskGreater activationBOLD activityBehavioral engagementCingulate cortexPrecuneusBrain regionsLow-frequency fluctuationsFractional amplitudeBrain imagingSeed regionIndependent component analysisEngagement