2023
The effects of cocaine use severity and abstinence on behavioral performance and neural processes of response inhibition
Li G, Zhang Z, Zhang Y, Tang X, Li C. The effects of cocaine use severity and abstinence on behavioral performance and neural processes of response inhibition. Psychiatry Research Neuroimaging 2023, 336: 111734. PMID: 37871409, DOI: 10.1016/j.pscychresns.2023.111734.Peer-Reviewed Original ResearchConceptsDays of abstinenceStop-signal reaction timeHealthy controlsCocaine dependenceSuperior temporal gyrusCocaine use severityStop-signal taskCocaine useResponse inhibitionUse severityBilateral superior temporal gyrusFunctional magnetic resonanceWhole-brain regressionNeural processesPoor response inhibitionInhibition dysfunctionCerebral markersTemporal gyrusSTG activityAbstinenceSuccess trialsSeverityNeural mechanismsInhibitionBehavioral performance
2020
Gray matter volumetric correlates of behavioral activation and inhibition system traits in children: An exploratory voxel-based morphometry study of the ABCD project data
Ide JS, Li HT, Chen Y, Le TM, Li CSP, Zhornitsky S, Li CR. Gray matter volumetric correlates of behavioral activation and inhibition system traits in children: An exploratory voxel-based morphometry study of the ABCD project data. NeuroImage 2020, 220: 117085. PMID: 32592852, PMCID: PMC7572877, DOI: 10.1016/j.neuroimage.2020.117085.Peer-Reviewed Original ResearchMeSH KeywordsBrainChildChild BehaviorFemaleGray MatterHumansImage Processing, Computer-AssistedInhibition, PsychologicalMagnetic Resonance ImagingMaleOrgan SizeConceptsBehavioral activation systemBehavioral inhibition systemGray matter volumeHigher BAS scoresVentral striatumBAS scoresInhibition systemBIS scoresInferior frontal cortexFundamental behavioral traitsTwins/siblingsRight anterior insulaHigher BIS scoresNeural correlatesDevelopmental neuroscienceAnterior insulaVolumetric correlatesVoxel-based morphometry studyInternalizing psychopathologyCerebral basisVoxel-based morphometryBehavioral activationVentral caudateAvoidance traitsMatter volume
2019
Neural correlates of reward-directed action and inhibition of action
Le TM, Zhang S, Zhornitsky S, Wang W, Li CR. Neural correlates of reward-directed action and inhibition of action. Cortex 2019, 123: 42-56. PMID: 31747630, DOI: 10.1016/j.cortex.2019.10.007.Peer-Reviewed Original ResearchMeSH KeywordsBrainBrain MappingFrontal LobeInhibition, PsychologicalMagnetic Resonance ImagingRewardConceptsRostral anterior cingulate cortexInhibition of actionGo trialsReward-directed actionGoal-directed actionsInferior parietal cortexMiddle frontal cortexAnterior cingulate cortexMain effectSignificant main effectVisual attentionNeural correlatesGo taskResponse executionReward valuationNeural processesBrain activationHealthy human adultsNeural responsesReward magnitudeConjunction analysisLarge rewardDorsal ACCCingulate cortexParietal cortexInterdependent Neural Correlates of Reward and Punishment Sensitivity During Rewarded Action and Inhibition of Action
Le TM, Wang W, Zhornitsky S, Dhingra I, Zhang S, Li CR. Interdependent Neural Correlates of Reward and Punishment Sensitivity During Rewarded Action and Inhibition of Action. Cerebral Cortex 2019, 30: 1662-1676. PMID: 31667492, PMCID: PMC7132903, DOI: 10.1093/cercor/bhz194.Peer-Reviewed Original ResearchMeSH KeywordsAdultAvoidance LearningFemaleHumansIndividualityInhibition, PsychologicalMalePunishmentReinforcement, PsychologyRewardYoung AdultConceptsInhibition of actionNeural correlatesReinforcement Sensitivity TheoryRostral anterior cingulate cortexMiddle frontal gyrusAnterior cingulate cortexPunishment sensitivityReinforcement sensitivityMFG activityIndividual differencesNeural processesReward QuestionnaireTrait sensitivityBrain correlatesNeural substratesFrontal gyrusGo responseRewarded actionsSensitivity theoryIncorrect responsesMediation analysisCingulate cortexRegional activationBehavioral approachAvoidance behaviorNeural correlates of enhanced response inhibition in the aftermath of stress
Chang J, Hu J, Li CR, Yu R. Neural correlates of enhanced response inhibition in the aftermath of stress. NeuroImage 2019, 204: 116212. PMID: 31546050, PMCID: PMC7509808, DOI: 10.1016/j.neuroimage.2019.116212.Peer-Reviewed Original ResearchConceptsInhibitory controlAcute stressMagnetic resonance imaging studySignal taskResonance imaging studyFunctional magnetic resonance imaging studyMiddle frontal gyrusTrier Social Stress TestControl conditionSignal reaction timeAftermath of stressSocial Stress TestImaging studiesCognitive functionDynamic causal modelingStress exposureEnhanced response inhibitionPilot studyFrontal gyrusLife stressNeural mechanismsStriatumResponse inhibitionNeural correlatesImmediate effectsReward sensitivity and electrodermal responses to actions and outcomes in a go/no-go task
Le TM, Wang W, Zhornitsky S, Dhingra I, Zhang S, Li CR. Reward sensitivity and electrodermal responses to actions and outcomes in a go/no-go task. PLOS ONE 2019, 14: e0219147. PMID: 31344045, PMCID: PMC6657849, DOI: 10.1371/journal.pone.0219147.Peer-Reviewed Original ResearchConceptsSkin conductance responsesGreater skin conductance responsesReward sensitivityIndividual differencesPhysiological arousalInhibition of actionGo taskAppetitive stimuliTrait sensitivityGo/Go responseConductance responsesSalient eventsBehavioral contingenciesIncorrect responsesElectrodermal responsesPsychophysiological researchAvoidance behaviorArousalSex differencesSuccess rateBehavioral factorsResponse windowSuch outcomesGeneral indexA consensus guide to capturing the ability to inhibit actions and impulsive behaviors in the stop-signal task
Verbruggen F, Aron AR, Band GP, Beste C, Bissett PG, Brockett AT, Brown JW, Chamberlain SR, Chambers CD, Colonius H, Colzato LS, Corneil BD, Coxon JP, Dupuis A, Eagle DM, Garavan H, Greenhouse I, Heathcote A, Huster RJ, Jahfari S, Kenemans JL, Leunissen I, Li C, Logan G, Matzke D, Morein-Zamir S, Murthy A, Paré M, Poldrack RA, Ridderinkhof KR, Robbins TW, Roesch M, Rubia K, Schachar RJ, Schall JD, Stock AK, Swann NC, Thakkar KN, van der Molen MW, Vermeylen L, Vink M, Wessel JR, Whelan R, Zandbelt BB, Boehler CN. A consensus guide to capturing the ability to inhibit actions and impulsive behaviors in the stop-signal task. ELife 2019, 8: e46323. PMID: 31033438, PMCID: PMC6533084, DOI: 10.7554/elife.46323.Peer-Reviewed Original ResearchImaging the effects of age on proactive control in healthy adults
Hu S, Job M, Jenks SK, Chao HH, Li CR. Imaging the effects of age on proactive control in healthy adults. Brain Imaging And Behavior 2019, 13: 1526-1537. PMID: 31011949, PMCID: PMC6812594, DOI: 10.1007/s11682-019-00103-w.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgingBrainFemaleFrontal LobeHumansInhibition, PsychologicalMagnetic Resonance ImagingMaleParietal LobePrefrontal CortexReaction TimeConceptsInferior occipital gyrusStop-signal reaction timePrefrontal cortexProactive controlProactive inhibitionOlder adultsReactive inhibitionSuperior parietal lobuleSequential effectsEffect of ageSignal reaction timeCaudate headDistinct neural processesParacentral lobuleTrial reaction timeVentromedial prefrontal cortexLateral prefrontal cortexHealthy adultsNeural changesNeural plasticityOccipital gyrusParietal lobuleReaction timeYoung adultsBelief Model
2018
Response inhibition and fronto-striatal-thalamic circuit dysfunction in cocaine addiction
Wang W, Worhunsky PD, Zhang S, Le TM, Potenza MN, Li CR. Response inhibition and fronto-striatal-thalamic circuit dysfunction in cocaine addiction. Drug And Alcohol Dependence 2018, 192: 137-145. PMID: 30248560, PMCID: PMC6200592, DOI: 10.1016/j.drugalcdep.2018.07.037.Peer-Reviewed Original ResearchStructural and functional cerebral bases of diminished inhibitory control during healthy aging
Hu S, Ide JS, Chao HH, Castagna B, Fischer KA, Zhang S, Li C. Structural and functional cerebral bases of diminished inhibitory control during healthy aging. Human Brain Mapping 2018, 39: 5085-5096. PMID: 30113124, PMCID: PMC6287913, DOI: 10.1002/hbm.24347.Peer-Reviewed Original ResearchConceptsProlonged stop signal reaction timeStop-signal reaction timeAge-related reductionInhibitory controlFunctional changesPrefrontal cortexAge-related diminutionSignal taskRight dorsolateral prefrontal cortexSame brain regionsFunctional magnetic resonance imagingMagnetic resonance imagingMedial prefrontal cortexInferior parietal cortexResponse inhibitionDorsolateral prefrontal cortexInferior frontal cortexDiminished inhibitory controlCerebral changesStructure-function associationsSignal reaction timeCaudate headAge-related differencesStop-signal taskFrontal cortexLevodopa improves response inhibition and enhances striatal activation in early-stage Parkinson's disease
Manza P, Schwartz G, Masson M, Kann S, Volkow ND, Li CR, Leung HC. Levodopa improves response inhibition and enhances striatal activation in early-stage Parkinson's disease. Neurobiology Of Aging 2018, 66: 12-22. PMID: 29501966, PMCID: PMC6436810, DOI: 10.1016/j.neurobiolaging.2018.02.003.Peer-Reviewed Original ResearchConceptsEarly-stage Parkinson's diseaseParkinson's diseaseDopaminergic medicationAdvanced Parkinson's diseaseStriatal activationResponse inhibitionRole of dopaminergicAge-matched controlsFunctional magnetic resonance imagingMagnetic resonance imagingExecutive functionLevodopa monotherapyMultiple medicationsMotor symptomsSignificant group differencesPD groupStop-signal taskAdvanced stageLevodopaResonance imagingMedicationsFunctional connectivityCritical executive functionMotor inhibitionPatients
2017
Distinct neural processes support post-success and post-error slowing in the stop signal task
Zhang Y, Ide JS, Zhang S, Hu S, Valchev NS, Tang X, Li CR. Distinct neural processes support post-success and post-error slowing in the stop signal task. Neuroscience 2017, 357: 273-284. PMID: 28627420, PMCID: PMC6359720, DOI: 10.1016/j.neuroscience.2017.06.011.Peer-Reviewed Original Research
2016
Methylphenidate Modulates Functional Network Connectivity to Enhance Attention
Rosenberg MD, Zhang S, Hsu WT, Scheinost D, Finn ES, Shen X, Constable RT, Li CS, Chun MM. Methylphenidate Modulates Functional Network Connectivity to Enhance Attention. Journal Of Neuroscience 2016, 36: 9547-9557. PMID: 27629707, PMCID: PMC5039242, DOI: 10.1523/jneurosci.1746-16.2016.Peer-Reviewed Original ResearchConceptsAttention-deficit/hyperactivity disorderSustained attentionWhole-brain connectivity patternsFunctional brain networksHyperactivity disorderBrain networksConnectivity patternsConnectome-based predictive modeling approachWhole-brain functional connectivity patternsWhole-brain functional connectivity networksSustained attention taskStop-signal taskDose of methylphenidateFunctional network connectivityCausal roleFunctional connectivity patternsHealthy adultsAttention taskCognitive abilitiesPromising neuromarkerNetwork strengthBehavioral predictionsADHD treatmentConnectivity signaturesFunctional connectivity networksDissociable Fronto-Operculum-Insula Control Signals for Anticipation and Detection of Inhibitory Sensory Cue.
Cai W, Chen T, Ide JS, Li CR, Menon V. Dissociable Fronto-Operculum-Insula Control Signals for Anticipation and Detection of Inhibitory Sensory Cue. Cerebral Cortex 2016, 27: 4073-4082. PMID: 27473319, PMCID: PMC6059112, DOI: 10.1093/cercor/bhw219.Peer-Reviewed Original ResearchConceptsInhibitory cuesInhibitory controlIndependent functional magnetic resonanceSensory cortexCausal influenceInferior frontal cortexMultiple sensory modalitiesFunctional magnetic resonanceAnterior insular cortexDynamic causal interactionsStrong causal influencesCue anticipationPrimary sensory cortexPrepotent responsesSalient stimuliSalient cuesSensory modalitiesTrial changesSensory cuesAdaptive behaviorCuesRight frontoRIFCExternal cuesHigher anticipationA dual but asymmetric role of the dorsal anterior cingulate cortex in response inhibition and switching from a non-salient to salient action
Manza P, Hu S, Chao HH, Zhang S, Leung HC, Li CS. A dual but asymmetric role of the dorsal anterior cingulate cortex in response inhibition and switching from a non-salient to salient action. NeuroImage 2016, 134: 466-474. PMID: 27126003, PMCID: PMC4912860, DOI: 10.1016/j.neuroimage.2016.04.055.Peer-Reviewed Original ResearchConceptsDorsal anterior cingulate cortexStop-signal reaction timeAnterior cingulate cortexSignal reaction timeCingulate cortexResponse inhibitionMotor inhibitionPre-supplementary motor areaRegional activationPre-SMA functionRegional brain activationMotor response inhibitionMotor areaStop trialsSalience processingBrain activationSalience detectionSuccess trialsSignal taskTrialsInhibitionSuccessful inhibitionInfrequent stimuliCortexActivationPower spectrum scale invariance as a neural marker of cocaine misuse and altered cognitive control
Ide JS, Hu S, Zhang S, Mujica-Parodi LR, Li CS. Power spectrum scale invariance as a neural marker of cocaine misuse and altered cognitive control. NeuroImage Clinical 2016, 11: 349-356. PMID: 27294029, PMCID: PMC4888196, DOI: 10.1016/j.nicl.2016.03.004.Peer-Reviewed Original ResearchConceptsPower spectrum scale invarianceCognitive controlInferior frontal gyrusNeural markersBehavioral adjustmentSupramarginal gyrusLeft inferior frontal gyrusFunctional magnetic resonance imagingFronto-parietal areasBlood oxygenation level-dependent (BOLD) signalCocaine misuseLevel-dependent signalCocaine-dependent adultsSignal taskFrontal gyrusFrontoparietal regionsPrefrontal cortexMagnetic resonance imagingConnectivity dynamicsBehavioral variablesCerebral activityCocaine addictionCocaine exposureCocaine dependenceDependent adultsAssociation of Drinking Problems and Duration of Alcohol Use to Inhibitory Control in Nondependent Young Adult Social Drinkers
Hu S, Zhang S, Chao HH, Krystal JH, Li CS. Association of Drinking Problems and Duration of Alcohol Use to Inhibitory Control in Nondependent Young Adult Social Drinkers. Alcohol Clinical And Experimental Research 2016, 40: 319-328. PMID: 26833431, PMCID: PMC4742397, DOI: 10.1111/acer.12964.Peer-Reviewed Original ResearchMeSH KeywordsAdultAlcohol DrinkingAlcoholismBrainCase-Control StudiesFemaleFunctional NeuroimagingHumansInhibition, PsychologicalMagnetic Resonance ImagingMaleSelf-ControlConceptsAlcohol Use Disorders Identification TestYears of drinkingStop-signal reaction timeAlcohol useAge-related changesAlcohol misuseInhibitory controlAUDIT scoresDrinking problemsNondependent drinkersProlonged stop signal reaction timeChronic alcohol useAnterior cingulate cortexPresupplementary motor areaDisorders Identification TestRight inferior frontal gyrusResponse inhibitionSuperior temporal gyrusYoung adult social drinkersFunctional magnetic resonanceAdult social drinkersSignal reaction timeCerebral responsesInferior frontal gyrusHigher AUDIT
2015
Independent component analysis of functional networks for response inhibition: Inter‐subject variation in stop signal reaction time
Zhang S, Tsai S, Hu S, Xu J, Chao HH, Calhoun VD, Li C. Independent component analysis of functional networks for response inhibition: Inter‐subject variation in stop signal reaction time. Human Brain Mapping 2015, 36: 3289-3302. PMID: 26089095, PMCID: PMC4545723, DOI: 10.1002/hbm.22819.Peer-Reviewed Original ResearchConceptsStop-signal reaction timeStop-signal taskCognitive controlSignal reaction timeResponse inhibitionStop successBeta weightsReaction timeCritical executive functionFunctional networksIndependent component analysisExecutive functionError trialsSignal taskComponent processesMotor preparationBrain networksBehavioral validityMotor regionsRace modelLinear modelingGeneral linear modelingLarge sampleIndependent componentsFMRIConflict anticipation in alcohol dependence — A model-based fMRI study of stop signal task
Hu S, Ide JS, Zhang S, Sinha R, Li CS. Conflict anticipation in alcohol dependence — A model-based fMRI study of stop signal task. NeuroImage Clinical 2015, 8: 39-50. PMID: 26106526, PMCID: PMC4473266, DOI: 10.1016/j.nicl.2015.03.008.Peer-Reviewed Original ResearchConceptsStop-signal reaction timeHealthy control individualsConflict anticipationAlcohol dependenceCognitive controlProactive controlSignal taskSequential effectsModel-based fMRI studyAlcohol consumptionStop signalPre-supplementary motor areaBilateral inferior parietal cortexPerigenual anterior cingulate cortexSignificant sequential effectInferior parietal cortexSignal reaction timeWhole-brain responsesAnterior cingulate cortexRecent alcohol consumptionNeural correlatesFMRI studyNeural markersMotor areaTrial onsetPerigenual anterior cingulate event-related potential precedes stop signal errors
Chang A, Chen CC, Li HH, Li CS. Perigenual anterior cingulate event-related potential precedes stop signal errors. NeuroImage 2015, 111: 179-185. PMID: 25700955, PMCID: PMC4511155, DOI: 10.1016/j.neuroimage.2015.02.017.Peer-Reviewed Original Research