2019
The effects of age on cerebral responses to self-initiated actions during social interactions: An exploratory study
Wang W, Zhornitsky S, Chao HH, Levy I, Joormann J, Li CR. The effects of age on cerebral responses to self-initiated actions during social interactions: An exploratory study. Behavioural Brain Research 2019, 378: 112301. PMID: 31644928, PMCID: PMC6893150, DOI: 10.1016/j.bbr.2019.112301.Peer-Reviewed Original ResearchConceptsSelf-initiated actionsSocial interactionSocial anxietyCyberball taskNeural processesOccipital cortexBall tossPregenual anterior cingulate cortexAnterior cingulate cortexSex differencesSocial exclusionAnxiety Scale scoresBehavioral performanceOrbitofrontal cortexCingulate cortexSubjective reportsBehavioral burdenEffect of ageObserved sex differencesYoung adultsCerebral responsesAge-related diminutionGame sessionsAnxietyCortexHypothalamic Responses to Cocaine and Food Cues in Individuals with Cocaine Dependence
Zhang S, Zhornitsky S, Le TM, Li CR. Hypothalamic Responses to Cocaine and Food Cues in Individuals with Cocaine Dependence. The International Journal Of Neuropsychopharmacology 2019, 22: 754-764. PMID: 31420667, PMCID: PMC6929672, DOI: 10.1093/ijnp/pyz044.Peer-Reviewed Original ResearchConceptsHealthy control participantsHypothalamic activationCocaine useCocaine-dependent participantsFood cuesCocaine addictionHypothalamic responseControl participantsCocaine Craving QuestionnaireRecent cocaine useFunctional magnetic resonance imagingMagnetic resonance imagingCue-related activationsInferior parietal cortexHypothalamic dysfunctionClinical variablesDopaminergic pathwaysTonic cravingFood intakeQuestionnaire scoresRodent studiesVisual cortexParietal cortexResonance imagingHypothalamus
2018
From eyes‐closed to eyes‐open: Role of cholinergic projections in EC‐to‐EO alpha reactivity revealed by combining EEG and MRI
Wan L, Huang H, Schwab N, Tanner J, Rajan A, Lam NB, Zaborszky L, Li C, Price CC, Ding M. From eyes‐closed to eyes‐open: Role of cholinergic projections in EC‐to‐EO alpha reactivity revealed by combining EEG and MRI. Human Brain Mapping 2018, 40: 566-577. PMID: 30251753, PMCID: PMC6338213, DOI: 10.1002/hbm.24395.Peer-Reviewed Original ResearchConceptsRole of acetylcholineAlpha reactivityOlder adultsVisual cortexYoung adultsFunctional connectivity increasesAlpha desynchronizationCortical acetylcholineCholinergic pathwaysCholinergic projectionsLeukoaraiosis volumeCholinergic systemBasal nucleusPosterior cortexFunctional MRICohortFunctional connectivityCognitive healthAcetylcholineConnectivity increasesSimultaneous EEG-fMRIAlpha rhythmCortexAdultsSeparate sessions
2009
Altered Impulse Control in Alcohol Dependence: Neural Measures of Stop Signal Performance
Li C, Luo X, Yan P, Bergquist K, Sinha R. Altered Impulse Control in Alcohol Dependence: Neural Measures of Stop Signal Performance. Alcohol Clinical And Experimental Research 2009, 33: 740-750. PMID: 19170662, PMCID: PMC2697053, DOI: 10.1111/j.1530-0277.2008.00891.x.Peer-Reviewed Original ResearchConceptsHealthy control subjectsFunctional magnetic resonance imagingAlcohol dependencePost-error behavioral adjustmentDorsolateral prefrontal cortexAlcohol urgesTrial reaction timePost-error slowingPrefrontal cortexLeft dorsolateral prefrontal cortexRight dorsolateral prefrontal cortexMagnetic resonance imagingImpulse controlStatistical parametric mappingStop errorAbstinent patientsControl subjectsNovel pharmacotherapiesSignal reaction timeTreatment outcomesFrontal cortexHC subjectsResonance imagingBehavioral adjustmentSubcortical structures