2016
The Effects of Methylphenidate on Resting-State Functional Connectivity of the Basal Nucleus of Meynert, Locus Coeruleus, and Ventral Tegmental Area in Healthy Adults
Kline RL, Zhang S, Farr OM, Hu S, Zaborszky L, Samanez-Larkin GR, Li CS. The Effects of Methylphenidate on Resting-State Functional Connectivity of the Basal Nucleus of Meynert, Locus Coeruleus, and Ventral Tegmental Area in Healthy Adults. Frontiers In Human Neuroscience 2016, 10: 149. PMID: 27148006, PMCID: PMC4834346, DOI: 10.3389/fnhum.2016.00149.Peer-Reviewed Original ResearchResting-state functional connectivityEffects of methylphenidateAttention deficit hyperactivity disorderLocus coeruleusPositive connectivityNegative connectivityFunctional connectivityBrain resting-state functional connectivityHealthy adultsDeficit hyperactivity disorderBasal nucleusDose of methylphenidateMiddle occipital gyrusSeed regionVTA/SNcVentral tegmental area/substantia nigraCognitive controlVentral tegmental areaHyperactivity disorderOccipital gyrusT-testCatecholaminergic signalingTwo-sample t-testMethylphenidatePrecentral gyrus
2011
Resting-State Functional Connectivity of the Medial Superior Frontal Cortex
Zhang S, Ide JS, Li CS. Resting-State Functional Connectivity of the Medial Superior Frontal Cortex. Cerebral Cortex 2011, 22: 99-111. PMID: 21572088, PMCID: PMC3236794, DOI: 10.1093/cercor/bhr088.Peer-Reviewed Original ResearchConceptsMedial superior frontal cortexSupplementary motor areaSuperior frontal cortexFunctional connectivityFrontal cortexMotor areaResting-state functional magnetic resonanceResting-state functional connectivityFrontal cortical functionPresupplementary motor areaFunctional magnetic resonanceSubthalamic nucleusSomatomotor areasCortical functionPreSMAAnterior partSignificant hemispheric asymmetryCaudateBehavioral tasksAnatomical boundariesCortexFuture studiesHemispheric asymmetryMagnetic resonanceSeed region
2009
A neural measure of behavioral engagement: Task-residual low-frequency blood oxygenation level-dependent activity in the precuneus
Zhang S, Li CS. A neural measure of behavioral engagement: Task-residual low-frequency blood oxygenation level-dependent activity in the precuneus. NeuroImage 2009, 49: 1911-1918. PMID: 19761851, PMCID: PMC2791356, DOI: 10.1016/j.neuroimage.2009.09.004.Peer-Reviewed Original ResearchConceptsBlood oxygenation level-dependent activityRegional brain activationLevel-dependent activityTask engagementNeural measuresNeural processesBrain activationPosterior cingulate cortexAttentional monitoringResponse inhibitionHuman cognitionPrefrontal activationSignal taskGreater activationBOLD activityBehavioral engagementCingulate cortexPrecuneusBrain regionsLow-frequency fluctuationsFractional amplitudeBrain imagingSeed regionIndependent component analysisEngagement