2020
KTN1 Variants Underlying Putamen Gray Matter Volumes and Parkinson’s Disease
Mao Q, Wang X, Chen B, Fan L, Wang S, Zhang Y, Lin X, Cao Y, Wu YC, Ji J, Xu J, Zheng J, Zhang H, Zheng C, Chen W, Cheng W, Luo X, Wang K, Zuo L, Kang L, Li CR, Luo X. KTN1 Variants Underlying Putamen Gray Matter Volumes and Parkinson’s Disease. Frontiers In Neuroscience 2020, 14: 651. PMID: 32655362, PMCID: PMC7324786, DOI: 10.3389/fnins.2020.00651.Peer-Reviewed Original ResearchPutamen gray matter volumesSubstantia nigra pars compactaGray matter volumeParkinson's diseaseMRNA expressionSingle nucleotide polymorphismsPD riskIndependent cohortMatter volumeDevelopment of PDPars compactaDopaminergic neuronsPutamenPutamen volumeSignificant associationPD associationsRisk allelesDiseaseSelective lossCohortGene variants
2017
The Effects of Age, from Young to Middle Adulthood, and Gender on Resting State Functional Connectivity of the Dopaminergic Midbrain
Peterson AC, Zhang S, Hu S, Chao HH, Li CR. The Effects of Age, from Young to Middle Adulthood, and Gender on Resting State Functional Connectivity of the Dopaminergic Midbrain. Frontiers In Human Neuroscience 2017, 11: 52. PMID: 28223929, PMCID: PMC5293810, DOI: 10.3389/fnhum.2017.00052.Peer-Reviewed Original ResearchSubstantia nigra pars compactaVentral tegmental areaAttention-deficit/ hyperactivity disorderState functional connectivityAge-related changesEffect of ageFunctional connectivityParahippocampal gyrusParkinson's diseaseMiddle adulthoodDopaminergic ventral tegmental areaBilateral angular gyrusOrbital frontal regionsBlood oxygenation level-dependent (BOLD) signalLevel-dependent signalPosterior orbital gyrusTime courseNeural basisDopaminergic midbrainHyperactivity disorderNeural mechanismsAngular gyrusPars compactaFrontal regionsDopaminergic structures
2015
Resting-State Functional Connectivity of the Locus Coeruleus in Humans: In Comparison with the Ventral Tegmental Area/Substantia Nigra Pars Compacta and the Effects of Age
Zhang S, Hu S, Chao HH, Li CR. Resting-State Functional Connectivity of the Locus Coeruleus in Humans: In Comparison with the Ventral Tegmental Area/Substantia Nigra Pars Compacta and the Effects of Age. Cerebral Cortex 2015, 26: 3413-3427. PMID: 26223261, PMCID: PMC4961017, DOI: 10.1093/cercor/bhv172.Peer-Reviewed Original ResearchConceptsVentral tegmental area/substantia nigra pars compactaSubstantia nigra pars compactaLocus coeruleusPars compactaFunctional connectivityResting-state functional connectivityCerebral functional connectivityNumerous animal studiesFronto-parietal cortexRight anterior insulaResting-state fMRI dataEffect of ageCerebral cortexNoradrenergic inputCognitive motor controlAnimal studiesCortex decreasesHealthy adultsCerebellum increasesMidbrain nucleiBilateral amygdalaMidbrain structuresAnterior insulaCognitive manifestationsMotor control