2020
Resting state hypothalamic and dorsomedial prefrontal cortical connectivity of the periaqueductal gray in cocaine addiction
Zhang S, Zhornitsky S, Wang W, Le TM, Dhingra I, Chen Y, Li C. Resting state hypothalamic and dorsomedial prefrontal cortical connectivity of the periaqueductal gray in cocaine addiction. Addiction Biology 2020, 26: e12989. PMID: 33300238, PMCID: PMC8614224, DOI: 10.1111/adb.12989.Peer-Reviewed Original ResearchConceptsPeriaqueductal grayPain circuitsDrug useCocaine addictionFunctional connectivityPrefrontal cortical connectivityState functional connectivityReward circuit dysfunctionRecent cocaine useHealthy control participantsInferior parietal cortexCompulsive drug useHabitual drug useCircuit dysfunctionCocaine withdrawalCocaine-dependent individualsCocaine cravingCortical connectivitySignificant anxietyDorsomedial prefrontalParietal cortexCocaine useIntrinsic connectivitySubcortical hubsDrug seekingThe Long‐Term Effects of Acupuncture on Hippocampal Functional Connectivity in aMCI with Hippocampal Atrophy: A Randomized Longitudinal fMRI Study
Li H, Wang Z, Yu H, Pang R, Ni H, Li C, Li K. The Long‐Term Effects of Acupuncture on Hippocampal Functional Connectivity in aMCI with Hippocampal Atrophy: A Randomized Longitudinal fMRI Study. Neural Plasticity 2020, 2020: 1-9. DOI: 10.1155/2020/6389368.Peer-Reviewed Original ResearchHippocampal functional connectivityAmnestic mild cognitive impairmentAcupuncture treatmentAcupuncture groupLong-term effectsFunctional magnetic resonance imagingFunctional connectivityControl groupAMCI patientsWhole-brain FC analysisResting-state functional magnetic resonance imagingResting-state fMRI scanningLongitudinal fMRI studyMagnetic resonance imagingHealthy control participantsMild cognitive impairmentMiddle temporal gyrusAcupuncture patientsHippocampal atrophyTherapeutic roleRight hippocampusBilateral caudateFC strengthAcupunctureCognitive decline
2019
Hypothalamic Responses to Cocaine and Food Cues in Individuals with Cocaine Dependence
Zhang S, Zhornitsky S, Le TM, Li CR. Hypothalamic Responses to Cocaine and Food Cues in Individuals with Cocaine Dependence. The International Journal Of Neuropsychopharmacology 2019, 22: 754-764. PMID: 31420667, PMCID: PMC6929672, DOI: 10.1093/ijnp/pyz044.Peer-Reviewed Original ResearchConceptsHealthy control participantsHypothalamic activationCocaine useCocaine-dependent participantsFood cuesCocaine addictionHypothalamic responseControl participantsCocaine Craving QuestionnaireRecent cocaine useFunctional magnetic resonance imagingMagnetic resonance imagingCue-related activationsInferior parietal cortexHypothalamic dysfunctionClinical variablesDopaminergic pathwaysTonic cravingFood intakeQuestionnaire scoresRodent studiesVisual cortexParietal cortexResonance imagingHypothalamus
2018
Disrupted Functional Connectivity of Cornu Ammonis Subregions in Amnestic Mild Cognitive Impairment: A Longitudinal Resting-State fMRI Study
Li H, Jia X, Qi Z, Fan X, Ma T, Pang R, Ni H, Li CR, Lu J, Li K. Disrupted Functional Connectivity of Cornu Ammonis Subregions in Amnestic Mild Cognitive Impairment: A Longitudinal Resting-State fMRI Study. Frontiers In Human Neuroscience 2018, 12: 413. PMID: 30420801, PMCID: PMC6216144, DOI: 10.3389/fnhum.2018.00413.Peer-Reviewed Original ResearchAmnestic mild cognitive impairmentMiddle temporal gyrusRight middle temporal gyrusState functional connectivityMild cognitive impairmentFunctional connectivityAMCI subjectsRight CA1Cornu ammonisLongitudinal resting-state fMRI studyCognitive impairmentCuneal cortexLongitudinal changesResting-State fMRI StudyState functional MRI scansDisrupted Functional ConnectivityLongitudinal cognitive assessmentsFunctional MRI scansGray matter volumeSubtle structural deficitsHealthy control participantsMiddle temporal cortexImportant neural markerCovariates of ageCA1 connectivity
2014
Cognitive Control in Opioid Dependence and Methadone Maintenance Treatment
Liao DL, Huang CY, Hu S, Fang SC, Wu CS, Chen WT, Lee TS, Chen PC, Li CS. Cognitive Control in Opioid Dependence and Methadone Maintenance Treatment. PLOS ONE 2014, 9: e94589. PMID: 24727743, PMCID: PMC3984179, DOI: 10.1371/journal.pone.0094589.Peer-Reviewed Original ResearchConceptsMethadone maintenance treatmentOpioid dependencePost-error slowingStop-signal reaction timePsychiatric comorbidityMaintenance treatmentCognitive controlAbstinence durationOpioid-dependent individualsResponse inhibitionHealthy control participantsMethadone treatmentSignal reaction timeCognitive dysfunctionMMT groupPsychiatric clinicSubstance misuseLonger abstinenceComorbiditiesHC participantsControl participantsDependent individualsSignal taskBehavioral adjustmentPublic health