2021
Lower prefrontal cortical synaptic vesicle binding in cocaine use disorder: An exploratory 11C‐UCB‐J positron emission tomography study in humans
Angarita GA, Worhunsky PD, Naganawa M, Toyonaga T, Nabulsi NB, Li C, Esterlis I, Skosnik PD, Radhakrishnan R, Pittman B, Gueorguieva R, Potenza MN, Finnema SJ, Huang Y, Carson RE, Malison RT. Lower prefrontal cortical synaptic vesicle binding in cocaine use disorder: An exploratory 11C‐UCB‐J positron emission tomography study in humans. Addiction Biology 2021, 27: e13123. PMID: 34852401, PMCID: PMC8891080, DOI: 10.1111/adb.13123.Peer-Reviewed Original ResearchConceptsCocaine use disorderAnterior cingulate cortexRecent cocaine useSynaptic densityMedial orbitofrontal cortexPrefrontal cortexCocaine useOrbitofrontal cortexUse disordersVentromedial prefrontal cortexPositron emission tomography scanPositron emission tomography studyEmission tomography scanSynaptic vesicle glycoprotein 2AHealthy control subjectsVolume of distributionEmission tomography studiesAcute cocaineControl subjectsTomography scanCocaine exposurePreclinical studiesHC subjectsDendritic spinesLifetime cocaine use
2017
Combined reality therapy and mindfulness meditation decrease intertemporal decisional impulsivity in young adults with Internet gaming disorder
Yao Y, Chen P, Li C, Hare T, Li S, Zhang J, Liu L, Ma S, Fang X. Combined reality therapy and mindfulness meditation decrease intertemporal decisional impulsivity in young adults with Internet gaming disorder. Computers In Human Behavior 2017, 68: 210-216. DOI: 10.1016/j.chb.2016.11.038.Peer-Reviewed Original ResearchDecisional impulsivityIGD subjectsHC subjectsTherapeutic targetYoung adultsInternet gaming disorderEnd of interventionPossible therapeutic targetReality therapyGroup behavioral interventionIGD severityMindfulness meditationBehavioral interventionsTherapySimilar time periodGaming disorderInterventionBalloon Analogue Risk TaskBaseline testBaselineSubjectsSeverityDisordersAdultsImpulsivity
2009
Altered Impulse Control in Alcohol Dependence: Neural Measures of Stop Signal Performance
Li C, Luo X, Yan P, Bergquist K, Sinha R. Altered Impulse Control in Alcohol Dependence: Neural Measures of Stop Signal Performance. Alcohol Clinical And Experimental Research 2009, 33: 740-750. PMID: 19170662, PMCID: PMC2697053, DOI: 10.1111/j.1530-0277.2008.00891.x.Peer-Reviewed Original ResearchConceptsHealthy control subjectsFunctional magnetic resonance imagingAlcohol dependencePost-error behavioral adjustmentDorsolateral prefrontal cortexAlcohol urgesTrial reaction timePost-error slowingPrefrontal cortexLeft dorsolateral prefrontal cortexRight dorsolateral prefrontal cortexMagnetic resonance imagingImpulse controlStatistical parametric mappingStop errorAbstinent patientsControl subjectsNovel pharmacotherapiesSignal reaction timeTreatment outcomesFrontal cortexHC subjectsResonance imagingBehavioral adjustmentSubcortical structures