2020
Age-Related Changes in the Neural Processes of Reward-Directed Action and Inhibition of Action
Le TM, Chao H, Levy I, Li CR. Age-Related Changes in the Neural Processes of Reward-Directed Action and Inhibition of Action. Frontiers In Psychology 2020, 11: 1121. PMID: 32587547, PMCID: PMC7298110, DOI: 10.3389/fpsyg.2020.01121.Peer-Reviewed Original ResearchInhibition of actionFunctional brain changesRostral anterior cingulate cortexWhole-brain multiple regressionAnterior cingulate cortexMiddle frontal gyrusAge-related changesFunctional magnetic resonanceBrain changesPostcentral gyrusCingulate cortexAnterior insulaFrontal gyrusTrialsProlonged response timeSuccess trialsGo trialsNeural activationReward-directed actionNegative modulationAgeAction inhibitionBrain substratesAge-related slowingReduced activity
2019
Neural correlates of reward-directed action and inhibition of action
Le TM, Zhang S, Zhornitsky S, Wang W, Li CR. Neural correlates of reward-directed action and inhibition of action. Cortex 2019, 123: 42-56. PMID: 31747630, DOI: 10.1016/j.cortex.2019.10.007.Peer-Reviewed Original ResearchConceptsRostral anterior cingulate cortexInhibition of actionGo trialsReward-directed actionGoal-directed actionsInferior parietal cortexMiddle frontal cortexAnterior cingulate cortexMain effectSignificant main effectVisual attentionNeural correlatesGo taskResponse executionReward valuationNeural processesBrain activationHealthy human adultsNeural responsesReward magnitudeConjunction analysisLarge rewardDorsal ACCCingulate cortexParietal cortex
2012
The effects of age on cerebral activations: internally versus externally driven processes
Hu S, Chao H, Winkler AD, Li CS. The effects of age on cerebral activations: internally versus externally driven processes. Frontiers In Aging Neuroscience 2012, 4: 4. PMID: 22536185, PMCID: PMC3334814, DOI: 10.3389/fnagi.2012.00004.Peer-Reviewed Original ResearchFunctional magnetic resonance imagingCerebral activationRegional brain activationAge-related decreaseCognitive processesPrepotent responsesPsychological constructsCognitive functioningSignal taskBrain activationGo trialsFMRI dataGo signalSE trialsEffect of ageImaging literatureYoung adultsStop signalHealthy adultsInfluence of ageSeeming inconsistencyAdultsMagnetic resonance imagingYears of ageFunctioning
2009
Functional Connectivity Delineates Distinct Roles of the Inferior Frontal Cortex and Presupplementary Motor Area in Stop Signal Inhibition
Duann JR, Ide JS, Luo X, Li CS. Functional Connectivity Delineates Distinct Roles of the Inferior Frontal Cortex and Presupplementary Motor Area in Stop Signal Inhibition. Journal Of Neuroscience 2009, 29: 10171-10179. PMID: 19675251, PMCID: PMC2769086, DOI: 10.1523/jneurosci.1300-09.2009.Peer-Reviewed Original ResearchConceptsMotor response inhibitionBasal ganglia circuitryPresupplementary motor areaInferior prefrontal cortexStop-signal inhibitionMotor areaRight inferior prefrontal cortexPrefrontal cortexResponse inhibitionSignal inhibitionRecent imaging literaturePrimary motor cortexMedial prefrontal cortexInferior frontal cortexMotor cortexFrontal cortexCortical areasPrimary siteVentral attention systemPreSMAGreater effective connectivityCortexFunctional interconnectivityPsychophysiological interactionGo trials