2018
Levodopa improves response inhibition and enhances striatal activation in early-stage Parkinson's disease
Manza P, Schwartz G, Masson M, Kann S, Volkow ND, Li CR, Leung HC. Levodopa improves response inhibition and enhances striatal activation in early-stage Parkinson's disease. Neurobiology Of Aging 2018, 66: 12-22. PMID: 29501966, PMCID: PMC6436810, DOI: 10.1016/j.neurobiolaging.2018.02.003.Peer-Reviewed Original ResearchConceptsEarly-stage Parkinson's diseaseParkinson's diseaseDopaminergic medicationAdvanced Parkinson's diseaseStriatal activationResponse inhibitionRole of dopaminergicAge-matched controlsFunctional magnetic resonance imagingMagnetic resonance imagingExecutive functionLevodopa monotherapyMultiple medicationsMotor symptomsSignificant group differencesPD groupStop-signal taskAdvanced stageLevodopaResonance imagingMedicationsFunctional connectivityCritical executive functionMotor inhibitionPatients
2015
Independent component analysis of functional networks for response inhibition: Inter‐subject variation in stop signal reaction time
Zhang S, Tsai S, Hu S, Xu J, Chao HH, Calhoun VD, Li C. Independent component analysis of functional networks for response inhibition: Inter‐subject variation in stop signal reaction time. Human Brain Mapping 2015, 36: 3289-3302. PMID: 26089095, PMCID: PMC4545723, DOI: 10.1002/hbm.22819.Peer-Reviewed Original ResearchConceptsStop-signal reaction timeStop-signal taskCognitive controlSignal reaction timeResponse inhibitionStop successBeta weightsReaction timeCritical executive functionFunctional networksIndependent component analysisExecutive functionError trialsSignal taskComponent processesMotor preparationBrain networksBehavioral validityMotor regionsRace modelLinear modelingGeneral linear modelingLarge sampleIndependent componentsFMRI
2011
Functional networks for cognitive control in a stop signal task: Independent component analysis
Zhang S, Li C. Functional networks for cognitive control in a stop signal task: Independent component analysis. Human Brain Mapping 2011, 33: 89-104. PMID: 21365716, PMCID: PMC3674850, DOI: 10.1002/hbm.21197.Peer-Reviewed Original ResearchConceptsStop-signal taskCognitive controlFronto-parietal networkStop successError processingSignal taskComponent processesFunctional networksLeft fronto-parietal networkRight fronto-parietal networkSelf-referential processingCritical executive functionCortico-subcortical networksAttentional monitoringExecutive functionResponse inhibitionError trialsNeural processesIndependent component analysisBehavioral engagementMotor preparationMotor cortical networkCortical networksSE trialsLinear modeling